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| http://dx.doi.org/10.1111/all.13738 | DOI Listing |
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A health economic analysis of noninjectable epinephrine compared with intramuscular epinephrine.
Ann Allergy Asthma Immunol
December 2024
Section of Allergy and Immunology, Department of Pediatrics, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado.
Background: Noninjectable epinephrine to treat allergic reactions addresses an unmet need. Intranasal epinephrine is approved and a sublingual form is under development. Inhaled epinephrine is poorly studied for anaphylaxis.
View Article and Find Full Text PDFGALEN ANACARE consensus statement: Potential of omalizumab in food allergy management.
Clin Transl Allergy
November 2024
Division of Allergy and Immunology, Department of Dermatology, Allergy and Venerology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Article Synopsis
- IgE-mediated food allergies are the most common type, causing quick and serious reactions that affect patients' and caregivers' lives.
- Omalizumab is a humanized monoclonal antibody that binds to IgE, reducing allergic reactions, and has been approved by the FDA for treating these food allergies.
- The GALEN ANACARE Consensus Statement supports omalizumab's use based on a systematic review and expert agreement, noting it is currently the only drug that can significantly reduce IgE-mediated food allergic reactions, although more evidence is needed for stronger guideline recommendations.
A murine model of peanut-allergic asthma.
Front Allergy
April 2024
Department of Dermatology, University of Zurich, Zurich, Switzerland.
Objectives: Peanut allergy is an IgE-mediated food allergy that is associated with asthma in certain patients. With increasing prevalence, its great impact on the quality of life, and a lack of treatment options, the need for new therapy options is a given. Hence, models for research and development are required.
View Article and Find Full Text PDFPeanut origin traceability: A hybrid neural network combining an electronic nose system and a hyperspectral system.
Food Chem
July 2024
School of Automation Engineering, Northeast Electric Power University, Jilin 132012, China; Bionic Sensing and Pattern Recognition Team, Northeast Electric Power University, Jilin 132012, China; Advanced Sensor Research Institution, Northeast Electric Power University, Jilin 132012, China. Electronic address:
Article Synopsis
- - This study examines how peanuts from different regions vary in quality due to their natural environments and proposes a new method to assess this quality quickly and without damage using advanced technology.
- - The method combines an electronic nose system and a hyperspectral system to collect gas and spectral data from peanuts, utilizing a specialized module for processing this information.
- - A hybrid neural network called UnitFormer is created to analyze the combined data, achieving impressive accuracy (99.06%), precision (99.12%), and recall (99.05%), providing a reliable way to monitor peanut quality in the food market.
AIT 2023: Current innovation and future outlook.
Allergol Select
December 2023
Department of Clinical Immunology, Wroclaw Medical University, Wroclaw, and.
Although used for over 100 years, allergen immunotherapy (AIT) is still an indispensable tool in modern allergy managemen20t due to its potential to cure allergic diseases. Its current rapid development through the application of personalized and precision medicine approaches is strongly supported by advances in mHealth, component-resolved diagnosis (CRD)-based diagnostics, validation of novel biomarkers, advanced data management, and development of novel preparations. This review summarizes the key advances in the field and shows the perspectives for further development of next-generation AIT treatments.
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