AI Article Synopsis
- The study aimed to compare the effectiveness of three different treatment regimens for pityriasis versicolor: fluconazole with ketoconazole, itraconazole alone, and ketoconazole alone.
- A total of 240 patients were divided into three groups, receiving different combinations of the drugs, with assessments made after 4 weeks.
- The results indicated that the fluconazole and ketoconazole combination led to the highest clinical cure rate at 62.4%, suggesting it is the most effective treatment option.
Article Abstract
Aim: Compare itraconazole alone, fluconazole combined with ketoconazole and ketoconazole in the treatment of patients with pityriasis versicolor.
Material And Methods: A group of 240 pityriasis versicolor patients (confirmed with KOH and culture) were classified into 3 groups: Fluconazole 300 mg a week and 2% ketoconazole foam twice a week for 2 weeks (Category I), Itraconazole 200 mg daily for one week (category II); Ketoconazole 2% foam daily for 2 weeks (Category 3). Clinical (colour of macule, scale, pruritus) and mycological assessment were done after 4 weeks of therapy.
Results: After 4 weeks of treatment, clinical cure was observed in 62.4% (Category I), 36.3% (Category II) and 37.5% (Category III).
Conclusion: It was reported in our study that the most effective regimen for PV patients is fluconazole 300 mg per week combined with ketoconazole 2% twice a week for 2 weeks.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364740 | PMC |
| http://dx.doi.org/10.3889/oamjms.2019.092 | DOI Listing |
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