AI Article Synopsis
- - Chronic myeloid leukaemia (CML) is becoming more common in pregnant women, despite its low overall incidence.
- - Treatment options for CML during pregnancy, such as tyrosine kinase inhibitors and interferon alpha, have potential risks for both mothers and their babies.
- - The authors highlight the need for established guidelines to better manage CML in pregnant patients, based on two reported cases with varying outcomes.
Article Abstract
Although the incidence of chronic myeloid leukaemia (CML) in pregnancy is low, it is progressively rising. The management strategies for CML patients during pregnancy include tyrosine kinase inhibitors, interferon alpha, leukapheresis and hydroxyurea, each of which has their own deleterious effects on the mother and foetus. There are virtually no accepted guidelines on the therapeutic options for these patients. We report two cases of CML which were reported to us during pregnancy, on imatinib, with different ultimate pregnancy outcomes. We do believe that it is high time professional bodies frame guidelines for the management of these patients.
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| http://dx.doi.org/10.1080/01443615.2018.1534815 | DOI Listing |
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