[Usefulness of photodynamic diagnosis in high-grade Bladder Cancer and subsequent BCG failure. Bibliographic review.].

Objectives: Bladder tumors are thesecond highest incidence urological tumor in the adultpopulation. In recent years, new techniques such as photodynamicdiagnosis have arisen in order to improvethe sensitivity for the detection of non muscle invasivebladder cancer (NMIBC). We intend to update the roleof photodynamic diagnosis in the diagnosis of NMIBC,in cases refractory to BCG and as a treatment in therecurrent bladder cancer.

Material And Method: We performed a descriptivestudy and bibliographic review on the usefulness of photratatodynamicdiagnosis in NMIBC, early recurrence andrefractoriness to BCG published in the universal medicalliterature.

Results: Photodynamic cystoscopy increases the detectionsensitivity for NMIBC, especially carcinoma in situ(CIS) from 15% to 30% according to the different seriespublished. Regarding high-grade bladder cancer recurrence,photodynamic therapy increases disease-freetime in 20% of patients. In the use of photodynamictechniques for the detection of CIS after BCG, studiesindicate an increase in sensitivity with an increase in therate of false positives.

Conclusion: Photodynamic diagnosis could improvesensitivity for the early detection of patients withCIS and/or T1G3. May be, at the same time, an alternativein the recurrence of bladder cancer, especiallyCIS.