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Comparison of transcutaneous bilirubin under patch-covered skin with total serum bilirubin in neonates undergoing phototherapy.
J Trop Pediatr
December 2024
Department of Neonatology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand 249203, India.
Transcutaneous bilirubinometry (TcB) is a recognized tool to monitor neonatal hyperbilirubinemia, demonstrating a high correlation with total serum bilirubin (TSB) before phototherapy. However, once phototherapy is started, TcB may become unreliable. To evaluate the correlation and agreement of TcB measured under variously patched skin at different sites (a coin over the sternum, eye shield over the forehead, and diaper area at the back) with TSB.
View Article and Find Full Text PDFSignal Quality in Continuous Transcutaneous Bilirubinometry.
Sensors (Basel)
September 2024
Department of Physics, Faculty of Science and Technology, NOVA University of Lisbon, Caparica Campus, 2829-516 Caparica, Portugal.
Bilirubin is a product of the metabolism of hemoglobin from red blood cells. Higher levels of bilirubin are a sign that either there is an unusual breaking down rate of red blood cells or the liver is not able to eliminate bilirubin, through bile, into the gastrointestinal tract. For adults, bilirubin is occasionally monitored through urine or invasive blood sampling, whilst all newborns are routinely monitored visually, or non-invasively with transcutaneous measurements (TcBs), due to their biological immaturity to conjugate bilirubin.
View Article and Find Full Text PDFTranscutaneous bilirubinometry for detecting jaundice in term or late preterm neonates.
Cochrane Database Syst Rev
May 2024
Cochrane South Africa, South African Medical Research Council, Cape Town, South Africa.
Background: The American Academy of Pediatrics and the Canadian Paediatric Society both advise that all newborns should undergo bilirubin screening before leaving the hospital, and this has become the standard practice in both countries. However, the US Preventive Task Force has found no strong evidence to suggest that this practice of universal screening for bilirubin reduces the occurrence of significant outcomes such as bilirubin-induced neurologic dysfunction or kernicterus.
Objectives: To evaluate the effectiveness of transcutaneous screening compared to visual inspection for hyperbilirubinemia to prevent the readmission of newborns (infants greater than 35 weeks' gestation) for phototherapy.
Machine Learning to Improve Accuracy of Transcutaneous Bilirubinometry.
Neonatology
December 2024
Department of Pediatrics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Introduction: This study aimed to develop models for predicting total serum bilirubin by correcting errors of transcutaneous bilirubin using machine learning based on neonatal biomarkers that could affect spectrophotometric measurements of tissue bilirubin.
Methods: This retrospective study included infants born at our hospital (≥36 weeks old, ≥2,000 g) between January 2020 and December 2022. Infants without a phototherapy history were included.
Can transcutaneous bilirubinometry safely be used to monitor rebound hyperbilirubinaemia after phototherapy in neonates ≥35 weeks' gestation? A prospective, comparative study.
Arch Dis Child Fetal Neonatal Ed
October 2024
Neonatal Unit, Princess Royal Maternity, Glasgow, UK
Introduction: There is insufficient evidence to determine if non-invasive transcutaneous bilirubin (TcB) measurement can replace serum bilirubin (SBR) in assessing rebound hyperbilirubinaemia after phototherapy.
Objective: To investigate if TcB can safely guide management of neonates after phototherapy.
Subjects: 100 well neonates ≥35 weeks' gestation who had received inpatient phototherapy.
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