Intracranial extension of temporomandibular joint (TMJ) ganglion cysts is very rare. Two previously reported cases presented clinically due to effects on cranial nerves and had obvious association with the TMJ on imaging. To the authors' knowledge, intracranial extension of a TMJ ganglion cyst presenting with seizures and mimicking a primary brain tumor has not been previously reported. The patient underwent resection of a presumptive primary cystic temporal lobe tumor, but the lesion had histopathological features of a nonneoplastic cyst with a myxoid content. He was followed with serial imaging for 5 years before regrowth of the lesion caused new episodes of seizures requiring a repeat operation, during which the transdural defect was repaired after the adjacent segment of the TMJ was curetted. A thorough review of all imaging studies and the histopathological findings from the repeat operation led to the correct diagnosis of a TMJ ganglion cyst. This case highlights an unusual presentation of this rare lesion, as well as its potential for recurrence. TMJ ganglion cysts should be included in the differential diagnosis of cystic tumors involving the anterior temporal lobe, presenting with or without seizures. Focused imaging evaluation of the TMJ can be helpful to rule out the possible role of associated TMJ lesions.
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http://dx.doi.org/10.3171/2018.10.JNS182665 | DOI Listing |
Int Immunopharmacol
January 2025
Department of Oral and Maxillofacial Surgery, State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education School and Hospital of Stomatology, Wuhan University, Wuhan, Hubei, China. Electronic address:
Background: Pain and disability are primary concerns for temporomandibular joint osteoarthritis (TMJOA) patients, and the efficacy of current treatments remains controversial. Overactive osteoclasts are associated with subchondral bone degeneration and pain in OA. The vacuolar H+-ATPase (V-ATPase) is crucial for differentiation and function in osteoclasts, but its role in TMJOA is not well defined.
View Article and Find Full Text PDFPain
December 2024
Program in Dental Biomedical Sciences, School of Dentistry, University of Maryland Baltimore, Baltimore, MD, United States.
Temporomandibular disorder (TMD) is the most prevalent painful condition in the craniofacial area. Recent studies have suggested that external or intrinsic trauma to the temporomandibular joint (TMJ) is associated with the onset of painful TMD in patients. Here, we investigated the effects of TMJ trauma through forced-mouth opening (FMO) in mice to determine pain behaviors and peripheral sensitization of trigeminal nociceptors in both sexes.
View Article and Find Full Text PDFJ Surg Case Rep
December 2024
Department of Oral and Maxillofacial Surgery, Yao Municipal Hospital, 1-3-1, Ryugecho, Yao-city, Oaka 581-0069, Japan.
Ganglions are pseudocysts that develop from part of the joint capsule or tendon sheath and are filled with synovial fluid. In this report, we describe a case of external auditory canal obstruction caused by a temporomandibular joint (TMJ) ganglion that was thought to be related to osteoarthritis. A 62-year-old man with the chief complaint of swelling of the anterior wall of the left external auditory canal underwent cystectomy at the Department of Otorhinolaryngology.
View Article and Find Full Text PDFJ Clin Invest
December 2024
Department of Pharmacology and Therapeutics, College of Pharmacy, University of Florida, Gainesville, United States of America.
Front Cell Neurosci
October 2024
Division of Oral Biology, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand.
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