AI Article Synopsis
- - The way early invertebrate and vertebrate embryos divide is crucial for determining how cells develop and how the body is organized.
- - A new computational modeling method is introduced to analyze the factors that influence where and how these divisions occur in 3D space.
- - This modeling technique aims to inspire and direct future experiments focused on understanding the processes that shape early embryo development.
Article Abstract
The division patterns of early invertebrate and vertebrate embryos are key to the specification of cell fates and embryo body axes. We here describe a generic computational modeling method to quantitatively test mechanisms which specify successive division position and orientation of eggs and early blastomeres in 3D. This approach should serve to motivate and guide future experimental work on the mechanisms controlling early embryo morphogenesis.
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| http://dx.doi.org/10.1007/978-1-4939-9009-2_24 | DOI Listing |
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