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Sleep apnea in acromegaly: a review on prevalence, pathogenetic aspects and treatment. | LitMetric

Sleep apnea in acromegaly: a review on prevalence, pathogenetic aspects and treatment.

Expert Rev Endocrinol Metab

b Department of Medical and Surgical Sciences, University of Brescia, Italy Endocrine Service, Montichiari Hospital, Via Ciotti 154, 25018 Montichiari, Brescia, Italy.

Published: January 2012

AI Article Synopsis

Article Abstract

Sleep apnea syndrome is a common complication of acromegaly with a negative impact on quality of life and survival. Obstructive sleep apnea is the prevailing form and is characterized by recurrent episodes of apnea and hypopnea owing to the total or partial collapse of the upper airways during sleep. The craniofacial deformations and the hypertrophy of upper airway soft tissue are responsible for its occurrence. Successful treatment of acromegaly can improve the severity of this complication, but can only seldom reverse it, particularly after a long time of active acromegaly. Thus, it is advisable to evaluate patients for sleep apnea syndrome at diagnosis and during treatment, and also when acromegaly is biochemically controlled. In selected cases, continuous positive airway pressure should be implemented to improve patient outcome.

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Source
http://dx.doi.org/10.1586/eem.11.82DOI Listing

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