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| http://dx.doi.org/10.1016/j.jdcr.2018.10.024 | DOI Listing |
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Silica-exposed patients with silicosis show shorter telomeres than do unexposed individuals: a pilot study in a population in southeastern Brazil.
J Bras Pneumol
January 2025
. Departamento de Biologia Geral, Universidade Federal Fluminense, Niterói (RJ) Brasil.
Objective: Silicosis is a pneumoconiosis characterized by fibrosis of the lung parenchyma caused by the inhalation of silica particles. Silica dust inhalation is associated with inflammation and induction of oxidative stress in the lungs. This oxidative stress affects telomeres, which are short tandem DNA repeats that cap the end of linear chromosomes.
View Article and Find Full Text PDFAn Incognito Standardized Patient Approach for Measuring and Reducing Intersectional Healthcare Stigma: A Pilot Cluster Randomized Control Trial.
J Acquir Immune Defic Syndr
November 2024
Department of Health Policy & Management, University of North Carolina, Chapel Hill, NC, USA.
Background: Consistent evidence shows stigma impedes healthcare access in people living with HIV (PLWH) and men who have sex with men (MSM). We evaluated the impact of a stigma reduction training for providers whose design was informed by direct observation of their clinical behaviors obtained through visits by incognito standardized patient (SP).
Setting: We conducted this study in in sexually transmitted infection clinics in Guangzhou, China.
Kynurenines and aerobic exercise capacity in chronic kidney disease: A cross-sectional and longitudinal study.
PLoS One
January 2025
Department of Clinical Physiology, Karolinska University Hospital, Stockholm, Sweden.
Background: The causes of reduced aerobic exercise capacity (ExCap) in chronic kidney disease (CKD) are multifactorial, possibly involving the accumulation of tryptophan (TRP) metabolites such as kynurenine (KYN) and kynurenic acid (KYNA), known as kynurenines. Their relationship to ExCap has yet to be studied in CKD. We hypothesised that aerobic ExCap would be negatively associated with plasma levels of TRP, KYN and KYNA in CKD.
View Article and Find Full Text PDFToxicological problems of tattoo removal: characterization of femtosecond laser-induced fragments of Pigment Green 7 and Green Concentrate tattoo ink.
Arch Toxicol
January 2025
STARTNETICS - Department of Chemical Science and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, 00133, Rome, Italy.
Femtosecond lasers represent a novel tool for tattoo removal as sources that can be operated at high power, potentially leading to different removal pathways and products. Consequently, the potential toxicity of its application also needs to be evaluated. In this framework, we present a comparative study of Ti:Sapphire femtosecond laser irradiation, as a function of laser power and exposure time, on water dispersions of Pigment Green 7 (PG7) and the green tattoo ink Green Concentrate (GC), which contains PG7 as its coloring agent.
View Article and Find Full Text PDFProfessional improbity: How Hermann J. Muller's ethics affected his science.
J Occup Environ Hyg
January 2025
Finance Department, University of Texas at Austin, Austin, Texas.
The present paper provides an assessment of how the scientific and national policy achievements/goals of Hermann J. Muller were impacted by his ethics and provides several documented episodes in which Muller acted unethically to promote his personal gain-at the expense of others-within the scientific community. Muller manipulated the scientific community in self-serving ways to suppress perspectives that challenged his own views on radiation-induced gene mutation, and hereditary and cancer risk assessment in ways that influenced his significant awards (e.
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