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Usual interstitial pneumonia: a clinically significant pattern, but not the final word.
Mod Pathol
May 2022
Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ, USA.
Usual interstitial pneumonia (UIP) is a concept that is deeply entrenched in clinical practice and the prognostic significance of UIP is well established, but the field continues to suffer from the lack of a true gold standard for diagnosing fibrotic interstitial lung disease (ILD). The meaning and usage of UIP have shifted over time and this term is prone to misinterpretation and poor diagnostic agreement. For pathologists, it is worth reflecting on the limitations of UIP and our true role in the care of patients with ILD, a controversial topic explored in two point-counterpoint editorials published simultaneously in this journal.
View Article and Find Full Text PDFCOUNTERPOINT: Should Surgical Lung Biopsy Still Be Performed for Interstitial Lung Disease Evaluation? No.
Chest
December 2021
Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark; Department of Diseases of the Thorax, G.B. Morgagni Hospital/Bologna University, Forlì, Italy.
COUNTERPOINT: Should Molecular and Genetic Biomarkers Be Used in the Initial Evaluation of Patients With Fibrotic ILD? No.
Chest
August 2019
Department of Pulmonary and Critical Care Medicine, Kaiser Permanente San Francisco, and the Department of Medicine, University of California San Francisco. Electronic address:
COUNTERPOINT: Should Transbronchial Cryobiopsies Be Considered the Initial Biopsy of Choice in Patients With a Possible Interstitial Lung Disease? No.
Chest
May 2019
Division of Pulmonary and Critical Care, Johns Hopkins University, Baltimore, MD.
COUNTERPOINT: Does Interstitial Pneumonia With Autoimmune Features Represent a Distinct Class of Patients With Idiopathic Interstitial Pneumonia? No.
Chest
February 2019
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
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