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[Refixation of osteochondral flake fractures after patellar dislocation-The parachute technique].
Oper Orthop Traumatol
December 2024
Sektion Sportorthopädie, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Deutschland.
Objective: Patellar dislocations are a common occurrence in orthopedic practice, often accompanied by osteochondral fractures of the retropatellar cartilage surface, known as flake fractures, in up to 58% of cases. The parachute technique represents a simple and cost-effective surgical option aimed at restoring osteochondral integration and preserving native cartilage.
Indications: Flake fracture of the patella with osteochondral fragments.
Low-Value Clinical Practices in Pediatric Trauma Care.
JAMA Netw Open
October 2024
Department of Social and Preventive Medicine, School of Medicine, Laval University, Québec City, Québec, Canada.
Article Synopsis
- The study highlights the significance of reducing low-value care in pediatric trauma, suggesting that it can enhance patient experiences and outcomes while minimizing unnecessary healthcare resource use.* -
- A retrospective cohort study involving over 10,700 children admitted to trauma centers in a Canadian province was conducted to identify and assess low-value practices in pediatric trauma care.* -
- The research found 19 low-value practices, with five showing moderate to high frequency and variation across hospitals, indicating a need for standardized care to improve pediatric trauma treatment.*
[Past and present of endoscopic surgery and robotic surgery in treatment of breast diseases].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
July 2024
Department of General Surgery, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P. R. China.
Objective: To review the research progress related to endoscopic surgery and robotic surgery for breast diseases, aiming to provide references for clinical practice.
Methods: The recent domestic and international literature on endoscopic surgery and robotic surgery for breast diseases was reviewed, then the challenges in their development, the innovative evolution of endoscopic surgery combined with clinical practice by our team, and its clinical applications were summarized.
Results: Traditional endoscopic surgery, despite its advantages such as minimal invasiveness, good cosmetic outcomes, and high patient's satisfaction, has been limited in its development due to specific difficulties in establishing the operative field.
Infective Endocarditis-Challenging Management of an 8-Year-Old with Duchenne Dystrophy and Undiagnosed Congenital Heart Disease: A Case Report.
Antibiotics (Basel)
April 2023
Department of Neonatal Intensive Care, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Congenital heart disease (CHD) remains a predisposing cardiac condition for infective endocarditis (IE). Case report: We present the case of 8-year-old boy with no known pre-existing cardiac disease diagnosed with infective endocarditis (IE) with After admission, he underwent transthoracic echocardiography (TTE), which revealed the presence of Shone syndrome with a bicuspid valve, mitral parachute valve and severe aortic coarctation. He developed a paravalvular aortic abscess with severe aortic regurgitation and left ventricle (LV) systolic dysfunction for which he required a complex surgical intervention after six weeks of antibiotic treatment, consisting of Ross operation and coarctectomy, with a complicated postoperative course, cardiac arrest and ECMO support for five days.
View Article and Find Full Text PDFIndividualised dosing of anti-thymocyte globulin in paediatric unrelated allogeneic haematopoietic stem-cell transplantation (PARACHUTE): a single-arm, phase 2 clinical trial.
Lancet Haematol
February 2022
Pediatric Blood and Marrow Transplant Program, Princess Máxima Centre for Pediatric Oncology, Utrecht, Netherlands; Stem Cell Transplantation and Cellular Therapies, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Background: Anti-thymocyte globulin, which is used in the conditioning of haematopoietic stem-cell transplantation (HSCT) to prevent graft-versus-host disease (GVHD) and graft failure, has highly variable pharmacokinetics. Overexposure to anti-thymocyte globulin leads to poor CD4 T-cell immune reconstitution, which is associated with inferior overall survival. We hypothesised that individualised anti-thymocyte globulin dosing would promote CD4 immune reconstitution, while still preventing GVHD and graft failure.
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