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Purpose: Planning osteotomies is a task that surgeons do as part of standard surgical workflow. This task, however, becomes more difficult and less intuitive when a robot is tasked with performing the osteotomy. In this study, we aim to provide a new method for surgeons to allow for highly intuitive trajectory planning, similar to the way an attending surgeon would instruct a junior.
Methods: Planning an osteotomy, especially during a craniotomy, is performed intraoperatively using a sterile surgical pen or pencil directly on the exposed bone surface. This paper presents a new method for generating osteotomy trajectories for a multi-DOF robotic manipulator using the same method and relaying the penscribed cut path to the manipulator as a three-dimensional trajectory. The penscribed cut path is acquired using structured light imaging, and detection, segmentation, optimization and orientation generation of the Cartesian trajectory are done autonomously after minimal user input.
Results: A 7-DOF manipulator (KUKA IIWA) is able to follow fully penscribed trajectories with sub-millimeter accuracy in the target plane and perpendicular to it (0.46 mm and 0.36 mm absolute mean error, respectively).
Conclusions: The robot is able to precisely follow cut paths drawn by the surgeon directly onto the exposed boney surface of the skull. We demonstrate through this study that current surgical workflow does not have to be drastically modified to introduce robotic technology in the operating room. We show that it is possible to guide a robot to perform an osteotomy in much the same way a senior surgeon would show a trainee by using a simple surgical pen or pencil.
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http://dx.doi.org/10.1007/s11548-018-01905-x | DOI Listing |
J Am Chem Soc
December 2024
Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu 610064, People's Republic of China.
Narrowband fluorescent emitters are receiving significant attention due to the great potential for creating ultrahigh-definition organic light-emitting diode displays (UHD-OLED). Unveiling innovative mechanisms to design new high-performance narrowband fluorescent emitters is a concerted endeavor in both academic and industrial circles. Theoretical calculations reveal that the centrosymmetric dianilido-bipyridine boron difluoride framework (-DAPBF) exhibits significantly reduced structural relaxation compared to previously reported asymmetric structures with monofluoroboron cores, creating new opportunities for the development of narrowband fluorescent emitters.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
School of Material Science and Engineering, Shanghai University of Engineering Science, Shanghai 201620, P.R. China.
Soft actuators are limited by single-mode driving technology, which poses challenges in dealing with complex and multidimensional movements. In this study, a multiresponsive soft actuator was fabricated by integrating a microwrinkling structure into an MXene-based film, enabling programmable motions. To achieve this, we introduced -hexane into the film preparation process and utilized its rapid volatilization to accelerate the shrinkage difference between the film and the substrate.
View Article and Find Full Text PDFAdv Sci (Weinh)
December 2024
Department of Industrial and Materials Science, Division of Engineering Materials, Chalmers University of Technology, Gothenburg, SE-412 96, Sweden.
Simultaneous rheological, polarized light imaging, and small-angle X-ray scattering experiments (Rheo-PLI-SAXS) are developed, thereby providing unprecedented level of insight into the multiscale orientation of hierarchical systems in simple shear. Notably, it is observed that mesoscale alignment in the flow direction does not develop simultaneously across nano-micro lengthscales in sheared suspensions of rod-like chiral-nematic (meso) phase forming cellulose nanocrystals. Rather, with increasing shear rate, orientation is observed first at mesoscale and then extends to the nanoscale, with influencing factors being the aggregation state of the hierarchy and concentration.
View Article and Find Full Text PDFAdv Sci (Weinh)
December 2024
Guangdong Provincial Key Laboratory of Digestive Cancer Research, Digestive Diseases Center, Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, 518107, P. R. China.
Precise control of Cas12a activity is essential for the improvement of the detection limit of clinical diagnostics and the minimization of errors. This study addresses the challenge of controlling Cas12a activity, especially in the context of nucleic acid detection where the inherent incompatibility between isothermal amplification and CRISPR reactions complicates accurate diagnostics. An RNA G-quadruplex (RG4) structure at the 5' end of crRNA is introduced to modulate Cas12a activity accurately without the need for chemical modifications.
View Article and Find Full Text PDFJ Phys Chem Lett
December 2024
State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Comonomer defects can induce semicrystalline polymers to form unique crystalline structures (., defect crystals), which can greatly influence the materials' physical properties. However, the formation mechanism and structural evolution of defect polymer crystals are not yet well understood.
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