Adzuki bean brown stem rot (BSR), caused by Cadophora gregata f. sp. adzukicola, and adzuki bean Fusarium wilt (AFW), caused by Fusarium oxysporum f. sp. adzukicola, are serious problems in Hokkaido, Japan, and have been managed using cultivars with multiple resistance. However, a limited number of adzuki bean varieties are resistant to these pathogens because of the frequent appearance of new races; thus, new sources of resistance have been sought in related Vigna spp., particularly in the section Angulares to which adzuki bean belongs. An analysis of selected Vigna accessions (JP81231 to JP235420) conserved in the Genebank of the National Institute of Agrobiological Sciences, Tsukuba, Japan, revealed wide variation in resistance spectra and resistance combinations, and eight disease response groups (A to H) were identified. Four of eight were newly detected response groups, suggesting the existence of novel resistance genes. Of 252 accessions from 26 species, 28 accessions in Vigna angularis var. nipponensis, V. hirtella, V. minima, and V. tenuicaulis (section Angulares) from group D, which were cross-compatible with adzuki bean, are expected to be potential sources of multiple resistance genes. They were resistant to all races of BSR and AFW pathogens examined.

Download full-text PDF

Source
http://dx.doi.org/10.1094/PDIS-06-11-0463DOI Listing

Publication Analysis

Top Keywords

adzuki bean
20
sources resistance
8
cadophora gregata
8
gregata adzukicola
8
fusarium oxysporum
8
oxysporum adzukicola
8
vigna spp
8
multiple resistance
8
response groups
8
resistance genes
8

Similar Publications

FLT3 mutations are among the most common genetic alterations in acute myeloid leukemia (AML) and are associated with poor prognosis. Significant advancements have been made in developing FLT3 inhibitors (FLT3Is), such as quizartinib, which have improved treatment outcomes in both newly diagnosed and relapsed/refractory AML. Resistance to FLT3Is remains a major clinical challenge, driven by diverse mechanisms including FLT3 point mutations, cellular escape pathways, and the influence of the bone marrow microenvironment.

View Article and Find Full Text PDF

The increasing frequency of heat stress events due to climate change disrupts all stages of plant growth, significantly reducing yields, especially in crops like mung bean (Vigna radiata (L.) R. Wilczek).

View Article and Find Full Text PDF

Prediction of Pt, Ir, Ru, and Rh complexes light absorption in the therapeutic window for phototherapy using machine learning.

J Cheminform

January 2025

PROMOCS Laboratory, Department of Chemistry and Chemical Technologies, University of Calabria, Arcavacata di Rende (CS), Italy.

Effective light-based cancer treatments, such as photodynamic therapy (PDT) and photoactivated chemotherapy (PACT), rely on compounds that are activated by light efficiently, and absorb within the therapeutic window (600-850 nm). Traditional prediction methods for these light absorption properties, including Time-Dependent Density Functional Theory (TDDFT), are often computationally intensive and time-consuming. In this study, we explore a machine learning (ML) approach to predict the light absorption in the region of the therapeutic window of platinum, iridium, ruthenium, and rhodium complexes, aiming at streamlining the screening of potential photoactivatable prodrugs.

View Article and Find Full Text PDF

The therapeutic window of antibody drug-conjugates (ADC) remains challenging due to safety issues such as interstitial lung disease (ILD) observed with specific deruxtecan-based ADCs. To avoid ILD, we designed M9140 by conjugating the maleimide-containing hydrophilic β-glucuronide linker to exatecan and our anti-CEACAM5 (CarcinoEmbryonic Antigen-related Cell Adhesion Molecule 5) specific antibody. Following repeated iv-infusion at 3 to 30 mg/kg of M9140 every 3 weeks, the pathological findings obtained in cynomolgus monkeys were confined to gastrointestinal and hematolymphoid tissues and resembled the toxicity of exatecan.

View Article and Find Full Text PDF

Gryllus madagascarensis (Orthoptera: Gryllidae) is a cricket species that shows promise to mitigate food insecurity and malnutrition. But whether this species will accept low- to no-cost weeds and agro by-products as feed, and how these feeds affect its performance, remains unknown. This study assessed the acceptability of 66 weed species and agro by-products (derived from a single plant species) by adult G.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!