The functioning and features of the new software package VAT (Virulence Analysis Tool) are introduced. VAT provides a range of methods for the analysis of plant pathosystems. The techniques are applicable to other binary data sets that are organized in large two-way tables, e.g., molecular marker data. The main features are data entry, descriptive tools, and inference statistics by resampling. About 50 well-established or newly developed indices allow a detailed diversity analysis of sexually and asexually reproducing populations. VAT facilitates a comprehensive, effective, and logically consistent evaluation and presentation of virulence and resistance data. A translation option simplifies the comparison of results from differently coded pathotypes. The software package comes with a detailed manual and is freely available on the internet at tau.ac.il/lifesci/departments/plant_s/members/kosman/VAT.html and at va-tipp.de .
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http://dx.doi.org/10.1094/PDIS-02-12-0114-SR | DOI Listing |
BMC Genomics
December 2024
The Key Lab of Animal Disease and Public Health / Luoyang Key Laboratory of Live Carrier Biomaterial and Animal Disease Prevention and Control, Henan University of Science and Technology, Luoyang, Henan, 471023, China.
The H3 subtype of avian influenza virus (AIV) stands out as one of the most prevalent subtypes, posing a significant threat to public health. In this study, a novel triple-reassortant H3N3 AIV designated A/chicken/China/16/2023 (H3N3), was isolated from a sick chicken in northern China. The complete genome of the isolate was determined using next-generation sequencing, and the AIV-like particles were confirmed via transmission electron microscopy.
View Article and Find Full Text PDFJ Agric Food Chem
December 2024
State Key Laboratory for Crop Stress Resistance and High-Efficiency Production and College of Life Sciences, Northwest A&F University, Yangling, Shaanxi 712100, China.
f. sp. () secretes a plethora of cell wall-degrading enzymes (CWDEs) to facilitate fungal invasion during infection.
View Article and Find Full Text PDFSignal Transduct Target Ther
December 2024
Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
Outer membrane (OM) lipoproteins serve vital roles in Gram-negative bacteria, contributing to their pathogenicity and drug resistance. For these lipoproteins to function, they must be transported from the inner membrane (IM), where they are assembled, to the OM by the ABC transporter LolCDE. We have previously captured structural snapshots of LolCDE in multiple states, revealing its dynamic conformational changes.
View Article and Find Full Text PDFMol Plant Pathol
December 2024
State Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, China.
Cytokinin signalling plays both positive and negative roles in plant resistance to pathogens. It is not clear whether the role of cytokinin changes at the different stages of pathogen infection. Arabidopsis thaliana sequentially exhibits distinct root morphological symptoms during Ralstonia solanacearum infection, which offers a good system to investigate function of cytokinin in the whole pathogen infection process.
View Article and Find Full Text PDFEmerg Microbes Infect
December 2024
Beijing Chaoyang District Center for Disease Control and Prevention, Beijing 100021, China.
Pertussis (or whooping cough) has experienced a global resurgence despite widespread vaccine efforts. In China, the incidence of pertussis has rapidly increased, particularly following the COVID-19 pandemic. Whole-genome sequencing analysis was performed on 60 strains isolated in Beijing from 2020 to 2023, and the sequences were compared with those of 635 strains from China and 943 strains from other countries.
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