AI Article Synopsis
- Riboswitches are non-coding segments that regulate gene expression in prokaryotes by changing shape when they bind to specific ligands.
- A new database called RiboD allows users to search and gather information on various riboswitches, including their locations and the genes they regulate.
- RiboD is freely available online, providing a valuable resource for studying riboswitches and gene regulation in bacteria and archaea.
Article Abstract
Summary: Riboswitches are cis-regulatory non-coding genomic segments that control the expression of downstream genes by undergoing conformational change upon ligand binding. We present a comprehensive database of prokaryotic riboswitches that allows the user to search for riboswitches using multiple criteria, extract information about riboswitch location and gene/operon it regulates. RiboD provides a very useful resource that can be utilized for the better understanding of riboswitch-based gene regulation in bacteria and archaea.
Availability And Implementation: RiboD can be freely accessed on the web at http://ribod.iiserkol.ac.in/.
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| http://dx.doi.org/10.1093/bioinformatics/btz093 | DOI Listing |
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