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Utility of Cand PCR in the Diagnosis of Vulvovaginal Candidiasis in Pregnant Women.
J Fungi (Basel)
December 2024
Laboratorio de Micología Molecular, Unidad de Investigación Biomédica, Hospital Regional de Alta Especialidad de Ixtapaluca, Instituto Mexicano de Seguro Social para el Bienestar (IMSS-BIENESTAR), Carretera Federal México-Puebla Km 34.5, Ixtapaluca CP 56530, Mexico.
Vulvovaginal candidiasis (VVC) can lead to multiple complications when it occurs during pregnancy, so it is necessary to diagnose it promptly for effective treatment. Traditional methods for identifying spp. are often too time-consuming and have limited specificity and sensitivity.
View Article and Find Full Text PDFHigh rates of potentially unnecessary topical antifungal prescribing in a large commercial health insurance claims database, United States.
J Am Acad Dermatol
January 2025
Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Efficacy and Safety of Intravaginal Estrogen in the Treatment of Atrophic Vaginitis: A Systematic Review and Meta-Analysis.
J Menopausal Med
August 2024
Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Article Synopsis
- Postmenopausal women often face genitourinary issues like vaginal dryness due to lower estrogen levels, with hormone replacement therapy being an effective treatment option.
- A comprehensive analysis of 18 randomized controlled trials (RCTs) found that intravaginal estrogen significantly increased beneficial superficial cells and reduced harmful parabasal cells, as well as improved vaginal pH and pain during intercourse (dyspareunia).
- Although estrogen therapy showed promise for treating vaginal atrophy and vaginitis, it did not significantly improve vaginal dryness, and while some side effects were noted, they were not significantly linked to the treatment.
Severe Vulvovaginal Candidiasis Associated With Sodium-Glucose Cotransporter 2 Inhibitors Use in Postmenopausal Women.
J Low Genit Tract Dis
September 2024
Northern Clinical School, University of Sydney, Sydney, New South Wales, Australia.
Article Synopsis
- A case series reported on 24 postmenopausal women experiencing severe vulvovaginal candidiasis while using sodium-glucose cotransporter-2 inhibitors (SGLT2i) for diabetes management.
- Patients presented with varying symptoms like vulvar itching, pain, and extensive skin changes, complicating timely diagnosis.
- Despite the severity of the infections, all patients improved with antifungal treatment, and those who stopped SGLT2i therapy saw resolution, highlighting the need for increased awareness among clinicians.
Collagen-Based Ovule Therapy Reduces Inflammation and Improve Cervical Epithelialization in Patients with Fungal, Viral, and Bacterial Cervico-Vaginitis.
Medicina (Kaunas)
August 2023
Hospital of National Relevance "A. Cardarelli", 80113 Naples, Italy.
: Vulvovaginal infections pose significant health challenges for women, necessitating effective treatment approaches. This retrospective observational study aimed at investigating the efficacy of collagen-based vaginal ovules therapy, specifically Plurigin Ovules, in restoring cervical epithelialization and reducing inflammation in mycotic, viral, and bacterial cervico-vaginitis. : A total of 398 women with cervico-vaginitis were included in the study, categorized into three groups: bacterial cervico-vaginitis (Group A), viral cervico-vaginitis (Group B), and fungal cervico-vaginitis (Group C).
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