The objective of the present study was to elucidate the influence of the age of the child, its location in the passenger compartment of the vehicle, and the application of the safety seat belts on the frequency of the injuries inflicted to the children involved in the motor vehicle traffic accidents. The analysis of the relevant clinical materials has demonstrated the non-uniform influence of the factors being evaluated on the specific features of the injuries to the different parts of the children's body. The age of the child was found to have the most pronounced effect on the character of the injuries. Direct correlation was documented between the age and the frequency and severity of the injuries to the body and bone of the lower legs whereas the frequency and severity of the fractures of the femoral bones as well as of the craniocerebral traumas showed inverse correlation with the age. The bones of the upper arm and the forearm are most frequently fractured in the 3-6-year-old children. The location of the child in the passenger compartment at the moment of the accident also influences the character of the injury. The front seat passengers most frequently suffer the severe injuries to the head and the fractures of the lower extremities. The injuries to the body and the fractures of the upper extremities occur more frequently in the children occupying the back seats. Fixation of the children with the safety belts is an important factor having the influence on the frequency and severity of the injuries caused to the body and the lower extremities in the children in the passenger compartment of a car. The absence of fixation increases the occurrence of injuries to the internal organs of the chest and abdominal cavities and of the fractures of the thoracic and pelvic bones. Moreover, the frequency of fractures of the femoral, mid- and lower leg bones increases.
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http://dx.doi.org/10.17116/sudmed2019620114 | DOI Listing |
Mol Cancer Ther
November 2024
University of California, Los Angeles, Los Angeles, CA, United States.
The treatment of non-small cell lung cancer has made major strides with the use of immune checkpoint inhibitors, but there remains a significant need for therapies that can overcome immunotherapy resistance. Dendritic cell (DC) vaccines have been proposed as a therapy that can potentially enhance the antitumor immune response. We have embarked on a phase I clinical trial of a vaccine consisting of monocyte-derived DCs (moDCs) modified to express the chemokine CCL21 (CCL21-DC) given in combination with pembrolizumab.
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September 2024
Design Institute of Hunan University, Changsha, 410082, Hunan, China.
Bioaerosols in public transportation systems raise critical environmental concerns, seriously threatening passenger health and safety. In this study, we investigate the spread characteristics of bioaerosols in a standard type-B subway compartment using both air sampling and sediment sampling methods. Additionally, without compromising indoor passenger comfort, two self-designed air purification devices, based on intense field dielectric (IFD) and dielectric barrier discharge (DBD) technologies, respectively, are successfully applied for the improvement of the subway air quality.
View Article and Find Full Text PDFHeliyon
September 2024
Department of Mechanical Engineering, Sakarya University of Applied Sciences, Sakarya, 54187, Turkey.
This study aimed to investigate the effect of changing the indoor unit air flow rate on the performance of an automobile heat pump with a suction line heat exchanger. Using a four-way valve, the automotive heat pump system was developed by reversing the refrigerant direction in the automobile air conditioning system, excluding the compressor. A suction line heat exchanger was added to the test system to enhance heat transfer between the liquid and suction lines of the automotive heat pump system.
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July 2024
Paul Scherrer Institute, PSI Center for Energy and Environmental Sciences, PSI, 5232, Villigen, Switzerland.
Metal azides are highly energetic materials that release a large amount of gas upon detonation. They also release metal particles, generating an aerosol. The most common azide is sodium azide (NaN), which is used nowadays in car airbags.
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May 2024
Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227 Dortmund, Germany; Centre for Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany. Electronic address:
Liquid-liquid phase separation (LLPS) of putative assembly scaffolds has been proposed to drive the biogenesis of membraneless compartments. LLPS scaffolds are usually identified through in vitro LLPS assays with single macromolecules (homotypic), but the predictive value of these assays remains poorly characterized. Here, we apply a strategy to evaluate the robustness of homotypic LLPS assays.
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