The second corresponding author Dr. Xiaochun Yu is only affiliated with [3] Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, 1500 E. Duarte Rd, Duarte, CA 91010, USA. He is not affiliated with [1] College of Life Sciences, Hebei University, Baoding 071002 Hebei, China.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363778 | PMC |
http://dx.doi.org/10.1038/s41389-019-0118-2 | DOI Listing |
EMBO Mol Med
November 2024
University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge, CB2 0RE, UK.
[Image: see text]
View Article and Find Full Text PDFInt J Mol Sci
August 2023
Department of Gynecology, Obstetrics and Gynecologic Oncology, Division of Gynecologic Oncology, Poznan University of Medical Sciences, Polna 33 St., 60-535 Poznan, Poland.
Cancer stem cells (CSCs) may contribute to an increased risk of recurrence in ovarian cancer (OC). Further research is needed to identify associations between CSC markers and OC patients' clinical outcomes with greater certainty. If they prove to be correct, in the future, the CSC markers can be used to help predict survival and indicate new therapeutic targets.
View Article and Find Full Text PDFInt J Biol Sci
June 2023
Department of Pharmacology, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, 050200, China.
[This corrects the article DOI: 10.7150/ijbs.53657.
View Article and Find Full Text PDFAging Cell
May 2023
Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
The intestinal epithelium consists of cells derived from continuously cycling Lgr5 intestinal stem cells (Lgr5 ISCs) that mature developmentally in an ordered fashion as the cells progress along the crypt-luminal axis. Perturbed function of Lgr5 ISCs with aging is documented, but the consequent impact on overall mucosal homeostasis has not been defined. Using single-cell RNA sequencing, the progressive maturation of progeny was dissected in the mouse intestine, which revealed that transcriptional reprogramming with aging in Lgr5 ISCs retarded the maturation of cells in their progression along the crypt-luminal axis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!