The SIR system for antimicrobial susceptibility testing (AST) has not changed over several decades. The European Committee on Antimicrobial Susceptibility Testing will from 1 January 2019 implement a new SIR definition, which will also apply in Sweden. The main change is that the I-group (previously »intermediate«) will be renamed as »susceptible, increased exposure«. If »I« is included in the AST report it does not mean that the antimicrobial agent should be avoided, but rather that the dosing regimen needs to compensate for the decreased susceptibility.
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