AI Article Synopsis
- The study explored how cognitive functions relate to obsessive-compulsive symptoms in schizophrenia, focusing on whether other schizophrenia symptoms influenced this relationship.
- Sixty-one schizophrenia patients were assessed using specific scales to measure their symptoms and cognitive abilities.
- Results showed a unique "obsessive paradox," where an inverse relationship shifted to a positive one regarding processing speed and obsessive symptoms, indicating that severe obsessive-compulsive symptoms might actually mitigate cognitive impairments.
Article Abstract
The objective of the study was to investigate the relationship between cognitive functions and obsessive-compulsive dimension in schizophrenia and a possible moderating effect of schizophrenia symptom dimensions on this association. Sixty-one schizophrenia patients were administered the Positive and Negative Syndrome Scale, the Yale-Brown Obsessive-Compulsive Scale (YBOCS), and the Matrics Consensus Cognitive Battery. A U-shaped curve described a gradual transition from an inverse association to a positive relationship between YBOCS and processing speed scores, along a severity gradient of obsessive dimension. This effect ("the obsessive paradox") was not moderated by other symptom dimensions. The present study suggests that severe obsessive-compulsive symptoms may participate to counterbalance processing speed impairment independently from other symptom dimensions. These results highlight the complexity of the relationship between cognitive and obsessive dimensions in schizophrenia.
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| http://dx.doi.org/10.1097/NMD.0000000000000932 | DOI Listing |
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