Effectiveness of embolic protection filter devices in stroke prevention during endovascular aortic arch repair in significant aortic atheroma patients.

Objectives: The objective of this study was to evaluate the effectiveness of embolic protection filter device in stroke prevention during hybrid endovascular arch repair in patients with significant aortic atheroma.

Methods: Twenty-two patients (20 men, mean age 79.0 years, mean logistic EuroSCORE 23.9%) with aortic arch/proximal descending aortic diseases and significant aortic atheroma (atheroma grade ≥ II) who were deemed unfit for conventional open surgery underwent endovascular aortic arch repair with protection of the supra-arch vessels using a balloon catheter and filter devices. The effectiveness in preventing stroke was evaluated by a postoperative neurological examination protocol, which was followed by neuroimaging with computed tomography/DW-magnetic resonance imaging (MRI) study in cases with neurological deficits.

Results: The atheroma grades of the aortic arch were II, III and IV in 36%, 14% and 50% of the patients, respectively. In total, 37 filter devices were placed in the supra-aortic vessels (5 brachiocephalic arteries, 23 carotid arteries, 5 subclavian arteries and 4 vertebral arteries). Technical success was achieved in all patients, and 30-day mortality was 4.5% (1/22 cases). Two (9.1%) cases showed neurological symptomatic stroke postoperatively. With DW-MRI examination, a major new region was detected in the filter-protected left carotid artery in one case and in the balloon-protected left vertebral artery in another case.

Conclusions: In high-risk patients with significant aortic arch atheroma, hybrid endovascular aortic arch repair with embolic protection using a filter device showed satisfactory early results. Filter protection could be an attractive adjunct manoeuvre for preventing critical stroke during endovascular arch repair.