AI Article Synopsis
- The study aimed to determine how allergies influence the clinical characteristics of chronic rhinosinusitis (CRS) in East Asians, involving 138 patients who had endoscopic sinus surgery.
- The results showed that about half of the patients tested positive for allergies, with allergic individuals being younger and having a higher eosinophil count compared to non-allergic patients, although CT scan and quality of life scores were similar between both groups.
- The findings suggest that allergies may worsen CRS progression, particularly correlated with higher eosinophil levels in patients with nasal polyps.
Article Abstract
Background: The role of allergy in the development of chronic rhinosinusitis (CRS) in East Asians is not clear.
Aims/objectives: The aim was to investigate the impact of allergies in the clinical characteristics of chronic rhinosinusitis.
Material And Methods: A total of 138 CRS patients who underwent endoscopic sinus surgery were included. A brief history of rhinosinusitis symptoms, blood eosinophil count, blood-specific allergen tests, computed tomography (CT) scan findings, Lund-Mackay (LM) CT scores, and Sino-Nasal Outcome Test (SNOT-22) Questionnaire scores, and sinoscopy findings at 3 and 6 months postoperatively.
Results: The ImmunoCAP test was positive in 71(51%) patients and negative in 67(49%) patients. The mean age of those who received endoscopic sinus surgery was 7-years younger in the allergic group compared with the non-allergic group (p = .008). The peripheral eosinophil count in the allergic group was higher than that of the non-allergic group (p = .008). The LM scores and SNOT-22 scores were not significantly different between the two groups. The recurrence rate of nasal polyps in the allergic group was higher but without statistical significance.
Conclusions And Significance: Allergy may accelerate the disease progression of CRS. The presence of the serum-specific IgE was correlated with peripheral eosinophil percentage, especially in the CRSwNP patients.
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| http://dx.doi.org/10.1080/00016489.2018.1552368 | DOI Listing |
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