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http://dx.doi.org/10.1002/mdc3.12299DOI Listing

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Article Synopsis
  • - Restless leg syndrome (RLS) is a neurological disorder that leads to a strong urge to move the legs, impacting the quality of life for many hemodialysis patients; this review focuses on exploring exercise as a treatment option.
  • - An analysis of eight studies found that aerobic and stretching exercises significantly reduced RLS severity and improved related issues like sleep quality and depression among hemodialysis patients over durations of eight weeks to six months.
  • - The findings suggest that exercise can be an effective non-pharmacological approach to managing RLS, potentially serving as an alternative or complement to dopamine agonists (DAs), which have side effects despite improving sleep quality.
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Detecting Agitated Behaviors in Nursing Home Residents With Dementia Using Electronic Medical Records.

J Am Med Dir Assoc

December 2024

Department of Health Services, Policy and Practice, School of Public Health, Brown University, Providence, RI, USA; Center for Gerontology and Healthcare Research, School of Public Health, Brown University, Providence, RI, USA; Center for Long-Term Care Quality and Innovation, School of Public Health, Brown University, Providence, RI, USA.

Objectives: Agitated behaviors (behaviors) are common in nursing home (NH) residents with Alzheimer's disease and related dementias (ADRD). Pragmatic trials of behavior management interventions rely on routinely collected Minimum Data Set (MDS) data to evaluate study outcomes, despite known underreporting. We describe a method to augment MDS-based behavioral measures with structured and unstructured data from NH electronic medical records (EMR).

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Introduction: This guideline establishes clinical practice recommendations for treatment of restless legs syndrome (RLS) and periodic limb movement disorder (PLMD) in adults and pediatric patients.

Methods: The American Academy of Sleep Medicine (AASM) commissioned a task force of experts in sleep medicine to develop recommendations and assign strengths based on a systematic review of the literature and an assessment of the evidence using the grading of recommendations assessment, development, and evaluation methodology. The task force provided a summary of the relevant literature and the certainty of evidence, the balance of benefits and harms, patient values and preferences, and resource use considerations that support the recommendations.

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Study Objectives: To determine any correlation between serum alpha-synuclein (α-syn) concentrations and restless legs syndrome (RLS), and to explore the impact of intravenous iron supplementation on serum α-syn levels.

Methods: We collected clinical data on 113 RLS patients in whom serum α-syn levels were quantified using an ELISA kit and compared to a group of 45 age-matched controls. A subset of nine RLS patients who received intravenous (IV) iron underwent pre- and post-treatment blood sampling to assess α-syn and ferritin response.

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