AI Article Synopsis
- A 66-year-old man with severe kidney dysfunction was admitted to the hospital due to numerous stubborn skin ulcers, initially suspected to be calciphylaxis due to systemic arterial calcification.
- A skin biopsy revealed the actual diagnosis of cholesterol crystal embolization, prompting treatments like hemodialysis and steroids.
- Unfortunately, the patient died from multiple intestinal perforations, with an autopsy confirming blockage of organ arterioles by cholesterol crystals, highlighting the critical link between skin ulcers and serious underlying conditions in chronic kidney disease patients.
Article Abstract
A 66-year-old man was admitted to our hospital because of multiple refractory skin ulcers. Based on his severe systemic arterial calcification and severe calcium-phosphate imbalance due to severe kidney dysfunction, we initially considered calciphylaxis. However, a skin biopsy provided a diagnosis of cholesterol crystal embolization. Although we initiated hemodialysis, steroid treatment, and low-density lipoprotein-cholesterol apheresis, he died of multiple intestinal perforation. An autopsy showed cholesterol crystals occluding multiple organ arterioles. This case suggests that skin ulcers in patients with chronic kidney disease may be an important diagnostic hallmark and may be associated with several serious diseases.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630139 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.2378-18 | DOI Listing |
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