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[Life-oriented Chemistry in Pharmaceutical Sciences: Frontiers of Functional Molecule Development for Advanced Molecular Imaging].
Yakugaku Zasshi
March 2024
Department of Pharmacology, Graduate School of Medicine, The University of Tokyo.
[Life-oriented Chemistry in Pharmaceutical Sciences].
Yakugaku Zasshi
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School of Pharmacy, Tokyo University of Pharmacy and Life Sciences.
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Yakugaku Zasshi
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Graduate School of Pharmaceutical Sciences, Kyushu University.
Induction pemetrexed and cisplatin followed by maintenance pemetrexed versus carboplatin plus paclitaxel plus bevacizumab followed by maintenance bevacizumab: a quality of life-oriented randomized phase III study in patients with advanced non-squamous non-small-cell lung cancer (ERACLE).
Clin Lung Cancer
November 2011
Division of Medical Oncology, Giovanni Paolo II Oncology Institute, Bari, Italy.
In advanced non-small-cell lung cancer (NSCLC), substantial similarities in terms of treatment efficacy and survival have emerged over the years between the different systemic chemotherapy regimens used. More recently, other topics such as histotype, maintenance therapy and quality of life have been explored to ameliorate this plateau. We present the treatment rationale and study design of the ERACLE (induction pEmetrexed and cisplatin followed by maintenance pemetRexed versus cArboplatin-paCLitaxel and bEvacizumab followed by maintenance bevacizumab) trial.
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