Revising the principal historical and clinical data available allows catatonia to be considered a kind of brain reaction unrelated to schizophrenia in restricted sense--i.e. to dementia praecox. Owing to the probabilities there are that malignant manifestations be developed, it is the author's opinion that it should be included into general medicine instead. Many cases including several catatonic attacks do not follow the usual course of dementia praecox. Moreover, true catatonic attacks frequency is quite low in chronic schizophrenia known as "catatonic schizophrenia". Thus, it seems necessary that relationships between catatonia, and spasmodic hysterical and epileptic symptoms be reevaluated accordingly. Electroconvulsive therapy is a very useful treatment, not only in simple catatonia attacks (which is a well-known application) but also on different malignant manifestations likely to arise during attacks.
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Psychol Rep
January 2025
School of Psychology, Faculty of Society and Design, Bond University, Gold Coast, QLD, Australia.
There has been a recent surge in schizotypy and metacognition research. Metacognition is an umbrella term for higher-order thought processes. Here, we focussed on maladaptive metacognitive beliefs, which are beliefs related to one's thought processes and often play an important role in the preponderance of psychological disorders.
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January 2025
Department of Psychiatry, Shin-Abuyama Hospital, Osaka Institute of Clinical Psychiatry, Takatsuki, 569-1041, Japan.
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January 2025
Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany.
Schizophrenia is a chronic and severe mental disorder. It is currently treated with antipsychotic drugs (APD). However, APD's work only in a limited number of patients and may have cognition impairing side effects.
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January 2025
Research Center Juelich, Institute of Neuroscience and Medicine 10, Research Center Juelich, Juelich, Germany.
Genetic variation in the α5 nicotinic acetylcholine receptor (nAChR) subunit of mice results in behavioral deficits linked to the prefrontal cortex (PFC). rs16969968 is the primary Single Nucleotide Polymorphism (SNP) in CHRNA5 strongly associated with nicotine dependence and schizophrenia in humans. We performed single cell-electrophysiology combined with morphological reconstructions on layer 6 (L6) excitatory neurons in the medial PFC (mPFC) of wild type (WT) rats, rats carrying the human coding polymorphism rs16969968 in Chrna5 and α5 knockout (KO) rats.
View Article and Find Full Text PDFBrain Stimul
January 2025
Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.
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