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Unique infrared thermographic profiles and altered hypothalamic neurochemistry associated with mortality in endotoxic shock.
Exp Neurol
December 2024
Department of Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University, Cleveland, OH, United States of America. Electronic address:
Neonatal sepsis results in significant morbidity and mortality, but early detection is clinically challenging. In a neonatal rat model of endotoxic shock, we identified unique infrared thermographic (IRT) profiles in skin temperature that could identify risk of later mortality. Ten-day old rats were placed in a thermally stable isolette and IRT images of cranial (T), scapula (T) and rump (T) skin temperature were obtained continuously for 8 h following an intraperitoneal injection of LPS (or saline).
View Article and Find Full Text PDFThe short term impact of radiofrequency ablative techniques and peripheral nerve block on thermoregulation in mouse models.
Sci Rep
December 2024
Department of Neuroscience and Cell Biology, Osaka University Graduate School of Medicine, Osaka, 565-0871, Japan.
This study investigated the impact of multiple nerve block methods (local anesthesia, conventional radiofrequency thermocoagulation [CRF], and pulsed radiofrequency [PRF]) on thermoregulation. Focusing on hypothalamic function, the effects of local anesthesia, CRF, and PRF on central and peripheral temperatures were analyzed and compared. Our findings revealed that all three nerve block groups cause a decrease in central temperature, with the CRF group exhibiting the most pronounced effect.
View Article and Find Full Text PDFPrevalence and determinants of neonatal hypothermia in a tertiary hospital, Gondar Ethiopia: a cross-sectional study.
Sci Rep
December 2024
Departemnt of Pediatrics and Child Health, School of Medicine, University of Gondar, P.O.Box: 196, Gondar, Ethiopia.
Neonatal hypothermia is a significant global problem of neonates with huge contribution of neonatal morbidity and mortality. Recognizing major contributors of neonatal hypothermia is very important in designing preventing methods which was the objective of our study. This was an institution-based cross-sectional study conducted on 339 neonates admitted to Neonatal Intensive Care Unit of University of Gondar Comprehensive Specialized Hospital over 6months.
View Article and Find Full Text PDFAssociation between body temperature and all-cause mortality in patients with sepsis: analysis of the MIMIC-IV database.
Eur J Med Res
December 2024
Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Background: Abnormal body temperature (fever or hypothermia) is a critical symptom in sepsis and is strongly associated with clinical prognosis and disease progression. Given the duality and variability of body temperature fluctuations throughout the disease course, further research is essential to refine clinical strategies for temperature management in sepsis patients.
Methods: We extracted clinical data of sepsis patients from the MIMIC-IV database.
Assessing Use and Familiarity of Enhanced Recovery After Surgery Elements in Pediatric Orthognathic Surgery.
J Craniofac Surg
October 2024
Department of Plastic Surgery, University of California, Irvine.
Enhanced recovery after surgery (ERAS) protocols have informed perioperative care across multiple surgical specialties, optimizing patient outcomes through surgical stress management and accelerated recovery. This study evaluates the familiarity and adoption of ERAS elements among craniofacial and oral and maxillofacial surgeons in pediatric orthognathic surgery, a field where a formal ERAS protocol has not been established. A closed-ended survey of 102 surgeons was conducted to assess familiarity with and utilization of 14 ERAS elements.
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