AI Article Synopsis
- * Red yeast rice (RYR) is a traditional Chinese food known for its ability to modulate lipids and enhance endothelial health, making it important for ASCVD prevention and treatment.
- * The article explores the molecular mechanisms through which RYR improves endothelial function, including its effects on endothelial reactivity, prevention of cell death in endothelial progenitor cells, reduction of oxidative stress, and anti-inflammatory properties.
Article Abstract
Atherosclerotic cardiovascular disease (ASCVD) is the deadliest disease in the world, with endothelial injury occurring throughout the course of the disease. Therefore, improvement in endothelial function is of essential importance in the prevention of ASCVD. Red yeast rice (RYR), a healthy traditional Chinese food, has a lipid modulation function and also plays a vital role in the improvement of endothelial reactivity and cardiovascular protection; thus, it is significant in the prevention and treatment of ASCVD. This article reviews the molecular mechanisms of RYR and its related products in the improvement of endothelial function in terms of endothelial reactivity, anti-apoptosis of endothelial progenitor cells, oxidative stress alleviation and anti-inflammation.
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| http://dx.doi.org/10.1016/S1875-5364(19)30009-3 | DOI Listing |
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