The first total syntheses of JBIR-06 and two analogous depsipeptides, 12-membered antimycin-class antibiotics, have been accomplished via Shiina macrolactonization. Comparison of the spectroscopic data of the synthesized compounds with those reported for natural products verified that the absolute configutation of the natural products was (2 S,4 S,6 S,7 R,14 S).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.orglett.8b03944 | DOI Listing |
Publication Analysis
Top Keywords
total syntheses
8
natural products
8
syntheses configuration
4
configuration assignments
4
assignments jbir-06
4
jbir-06 depsipeptides
4
depsipeptides total
4
syntheses jbir-06
4
jbir-06 analogous
4
analogous depsipeptides
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!