Objectives: The purposes of this study were to clarify (i) the prevalence of pneumoconiosis among young adults and (ii) the factors associated with pneumoconiosis among young adults to explore targeted solution for control of pneumoconiosis among young adults (aged 24-44 years).
Methods: The new cases diagnosed from 2001 to 2015 (extracted from the National Occupational Disease and Occupational Health Information Monitoring System) were involved in this research, including information of employer, patient's name, date of birth, gender, date of diagnosis, first year of dust exposure, duration of exposure, aggregation etc RESULTS: A total of 1519 pneumoconiosis cases were diagnosed among young adults (21.6% of overall cases). Silicosis was the most common type with acute process of disease. Compared with overall cases, the young patients had shorter duration of exposure, more stage II/III cases and higher aggravation rate; and were even more concentrated in small and medium enterprises where more migrant workers were employed and insufficient protective measures were used. Without further regulation, the prevalence of pneumoconiosis among young adults would bring not only disease suffering for 3000 individuals and their families, but also an annual economic loss up to 180 million yuan for Hebei province till 2025.
Conclusions: As a typical heavily industrialized province of China, Hebei has severe situation on pneumoconiosis among young adults. Special attention and effort on silica-contacting industries, small and medium enterprises, and migrant workers should be focused in future occupational supervision and regulation among young adults.
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http://dx.doi.org/10.1002/1348-9585.12029 | DOI Listing |
J Particip Med
January 2025
Division of Allergy & Pulmonary Medicine, Washington University School of Medicine, St Louis, MO, United States.
Background: Adolescents and young adults (AYA) with cystic fibrosis (CF) are at risk for deviating from their daily treatment regimen due to significant time burden, complicated daily therapies, and life stressors. Developing patient-centric, effective, engaging, and practical behavioral interventions is vital to help sustain therapeutically meaningful self-management.
Objective: This study aimed to devise and refine a patient-centered telecoaching intervention to foster self-management in AYA with CF using a combination of intervention development approaches, including an evidence- and theory-based approach (ie, applying existing theories and research evidence for behavior change) and a target population-centered approach (ie, intervention refinement based on the perspectives and actions of those individuals who will use it).
J Clin Psychiatry
January 2025
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York.
To provide proof-of-concept (PoC), dose-range finding, and safety data for BI 1358894, a TRPC4/5 ion channel inhibitor, in patients with borderline personality disorder (BPD). This was a phase 2, multinational, randomized, double-blind, placebo controlled trial. Patients were randomized to oral placebo or BI 1358894 (5 mg, 25 mg, 75 mg, or 125 mg) once daily in a 2.
View Article and Find Full Text PDFJ Clin Psychiatry
January 2025
Department of Psychiatry, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India, Department of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences, Bangalore, India
Cannabis use during pregnancy is increasing; the study of adverse outcomes in cannabis-exposed pregnancies is therefore important. Previous articles in this series described increased risks of maternal adverse outcomes, fetal adverse outcomes, birth defects in newborns, and autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in childhood. This article examines neuropsychiatric adverse outcomes in offspring gestationally exposed to cannabis.
View Article and Find Full Text PDFGac Med Mex
January 2025
Clínica de Hipertensión y Riesgo Cardiovascular, ISSSTESon, Hermosillo, Sonora. México.
Cardiovascular disease is the main cause of mortality in Mexico as well as the rest of the world, with dyslipidemia being one of the main risk factors. Despite the importance of its epidemiological impact, there is still -among primary care physicians- a lack of knowledge ranging from the basic concepts for diagnosis to the most recent recommendations for treatment. This document consisting of 10 questions is done by experts in this field.
View Article and Find Full Text PDFJ Neurosurg Case Lessons
January 2025
Neurosurgery Department, Palmetto General Hospital, Hialeah, Florida.
Background: Astroblastoma is an extremely rare tumor of the central nervous system, and its origin and validity as a different entity are still being debated. Because of its rarity and similarities to other glial neoplasms, it is often misdiagnosed, impacting treatment and outcomes.
Observations: Astroblastoma is very rare and mainly affects children and young adults.
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