Four new -geranyl flavonoids, paulownione D-G (-) were isolated from the 50% acetone-HO extract of the flowers of The structures of the compounds were determined by extensive spectroscopic analyses (UV, IR, HR-ESI-MS, 1D and 2D NMR). All of the compounds (-) exhibited potent protection effects in H9c2 cardiocytes against the lipopolysaccharide (LPS)-induced inflammation.
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http://dx.doi.org/10.1080/14786419.2018.1556263 | DOI Listing |
J Nat Prod
December 2024
Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
A comprehensive phytochemical investigation of root extract led to the isolation of two new geranylated xanthones ( and ), one new geranylated flavone (), one new flavanone (), and one unique benzopyran (), along with 16 known compounds. Structures of the new compounds were elucidated by a combination of spectroscopic and computational methods. Two different types of compounds, flavone and arylbenzofuran , displayed the most potent antityrosinase activity with IC values of 1.
View Article and Find Full Text PDFBMC Plant Biol
October 2024
Department of Food Science and Technology, Faculty of Agriculture, University of Tabriz, Tabriz, Iran.
Background: The utilization of nutrition management, has recently been developed as a means of improving the growth and production of phytochemical compounds in herbs. The present study aimed to improve the growth, physiological, and phytochemical characteristics of lemon balm (Melissa officinalis L.) using different NH (ammonium) to NŌ (nitrate) ratios (0:100, 25:75, 50:50, 75:25 and 100:0) under floating culture system (FCS).
View Article and Find Full Text PDFUnlabelled: Sweet potatoes are rich in flavonoids and phenolic acids, showing incomparable nutritional and health value. In this investigation, we comprehensively analyzed the secondary metabolite profiles in the flesh of different-colored sweet potato flesh. We determined the metabolomic profiles of white sweet potato flesh (BS), orange sweet potato flesh (CS), and purple sweet potato flesh (ZS) using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
View Article and Find Full Text PDFJ Inorg Biochem
September 2024
Department of Natural Drugs, Faculty of Pharmacy, Masaryk University, Palackého 1946/1, 612 00 Brno, Czech Republic.
Two copper(II) complexes containing diplacone (Hdipl), a naturally occurring C-geranylated flavanone derivative, in combination with bathophenanthroline (bphen) or 1,10-phenanthroline (phen) with the composition [Cu(bphen)(Hdipl)]⋅2HO (1) and {[Cu(phen)(Hdipl)]⋅1.25HO} (2) were prepared and characterized. As compared to diplacone, the complexes enhanced in vitro cytotoxicity against A2780 and A2780R human ovarian cancer cells (IC ≈ 0.
View Article and Find Full Text PDFChem Biodivers
July 2024
Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, P.O. Box 812, Yaoundé, Cameroon.
Phytochemical investigation of the methanol extract from the fruits of Macaranga monandra (Euphorbiaceae Muell. et Arg.) afforded one new geranylated 1',2'-dihydrophenanthrene and two new flavonoid derivatives, named macamondrin (1), macamondrione A (2) and B (3) respectively.
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