Bioactive phenolic acid-substituted glycoses and glycosides from rhizomes of .

J Asian Nat Prod Res

State Key Laboratory of Active Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050 , China.

Published: October 2019

Two rarely phenolic acid-substituted alloses () and one new glucoside (), as well as nine known compounds () were isolated from rhizomes of (L.) J. Sm. Structures of were established by extensively spectroscopic analyses (NMR, MS, etc.) and acid hydrolysis. All compounds were evaluated for the hepatoprotective activities against APAP-induced HepG2 cell damage. Compounds , -, exhibited significant hepatoprotective activities, even more strongly than positive control, bicycol. In addition, compounds and could reduce PC12 cell death induced by serum deprivation.

Download full-text PDF

Source
http://dx.doi.org/10.1080/10286020.2018.1563076DOI Listing

Publication Analysis

Top Keywords

phenolic acid-substituted
8
hepatoprotective activities
8
bioactive phenolic
4
acid-substituted glycoses
4
glycoses glycosides
4
glycosides rhizomes
4
rhizomes rarely
4
rarely phenolic
4
acid-substituted alloses
4
alloses glucoside
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!