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Exploring Hyperkalemia Risk in Frail Older Patients Using RAAS Inhibitors.
Drugs Aging
January 2025
Department of Geriatric Medicine, Jeroen Bosch Hospital, 's Hertogenbosch, The Netherlands.
Purpose: Renin-angiotensin-aldosterone system inhibitors (RAASi) are widely used in treatment of cardiovascular and renal disease. While effective, they pose a risk of hyperkalemia. In the general population, risk factors for hyperkalemia include chronic kidney disease, congestive heart failure, and use of medication affecting potassium balance.
View Article and Find Full Text PDFRe-evaluating the Need of Postoperative Blood Testing in Low-Risk Patients After Primary Elective Arthroplasty: A Single-Centre Retrospective Analysis.
Cureus
December 2024
Trauma and Orthopaedics, Wrightington Hospital, Wigan, GBR.
Introduction Increasing demand and financial burdens are placing significant strain on current health resources. To help ease pressures, there has been increased emphasis on improving patient flow and saving costs within the health service. Routine postoperative blood tests in otherwise healthy patients may add to delays and healthcare costs without influencing subsequent management.
View Article and Find Full Text PDFA Rare Cause of Neonatal Salt Wasting Syndrome: Clinical Management of a Case Diagnosed with Pseudohypoaldosteronism Due to a Novel Homozygous Variant in the Gene.
J Clin Res Pediatr Endocrinol
December 2024
Department of Pediatric Endocrinology, Akdeniz University Hospital, Antalya, Turkey.
Pseudohypoaldosteronism (PHA) is a rare disorder that, if not promptly recognized and treated, can lead to life-threatening hyperkalemia resulting in cardiac arrest and death. Systemic PHA is caused by variants that deactivate the epithelial sodium channel (ENaC) subunits. Management is challenging due to high-dose oral replacement therapy, and patients with systemic PHA require lifelong treatment.
View Article and Find Full Text PDFBiochemical profile of term neonates with perinatal asphyxia and their correlation with severity of asphyxia.
J Family Med Prim Care
November 2024
Department of Paediatrics, B.Y.L. Nair Hospital and Topiwala National Medical College, Mumbai, Maharashtra, India.
Background: Birth asphyxia is a major cause of neonatal mortality and neurological morbidity. This study was aimed to determine biochemical (sodium, potassium, and calcium) abnormalities and their correlation across different severities of perinatal asphyxia in term neonates.
Methods: This observational analytical study was conducted in term neonates with perinatal asphyxia admitted at the neonatal intensive care unit of a tertiary care centre for a period of 18 months.
[Potassium role in the human body and clinical implications of hyperkalemia].
G Ital Cardiol (Rome)
January 2025
U.O.C. Cardiologia 1-Emodinamica, Dipartimento Cardiotoracovascolare "A. De Gasperis", ASST Grande Ospedale Metropolitano Niguarda, Milano.
Potassium is the most represented intracellular electrolyte in the human body. Its extracellular levels are maintained within strict limits through different mechanisms, which constitute the homeostasis of potassium. Hyperkalemia is the most common electrolyte disorder in patients with cardiovascular disease.
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