Background: Adolescent idiopathic scoliosis (AIS) is a common orthopedic condition with a prevalence of 2%-3% in children aged 10-16 years. Conservative interventions remain controversial and are usually based on physical therapy exercises and treatments. Manual therapy techniques may also serve as adequate treatments for AIS due to their ability to improve range of motion and decrease muscle tone and pain.
Objective: To critically assess the current literature on the effectiveness of manual therapy methods used to treat AIS.
Methods: PubMed, PEDro, BioMed Central, and Google Scholar databases were searched from inception until December 2016 using keywords associated with scoliosis and manual therapy. Criteria for inclusion were studies investigating the effect of manual therapy methods on AIS treatment. We analyzed all published material with an emphasis on randomized controlled trials (RCT). Trials of any methodological quality written in English were included in the review.
Major Findings: Fourteen papers were reviewed, all presenting manual therapy treatments such as manipulation, mobilization, and soft tissue techniques used to treat AIS. All case studies showed a significant improvement, post-treatment, in most measured parameters. Observational studies showed mixed results. Only one RCT concluded manual therapy techniques were ineffective in improving trunk morphology and spine flexibility in AIS patients.
Conclusion: Case reports and small-scale clinical trials of poor methodological quality presented in this review did not allow us to draw a clear conclusion about the effectiveness of manual therapy in the treatment of AIS. On the other hand, they provide us a basis to assume that manual therapy techniques such as myofascial release and spinal manipulative techniques may potentially be effective in treating AIS in conjunction with other conservative treatments. Further high-quality studies are essential to determine the effectiveness of the different manual therapy techniques.
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http://dx.doi.org/10.1016/j.jbmt.2018.01.005 | DOI Listing |
Heliyon
January 2025
Department of Emergency, Dali Bai Autonomous Prefecture People's Hospital, Dali, Yunnan, 671000, China.
Background: Approximately 20%-50 % of individuals with autoimmune encephalitis (AE) demonstrate suboptimal responses to first-line therapies, leading to persistent neurological deficits and the need for second-line interventions. Although rituximab has shown potential as an alternative treatment in AE, the existing evidence remains insufficient. This study systematically evaluated and meta-analyzed the efficacy of rituximab in AE patients who either failed or exhibited inadequate responses to first-line treatments, aiming to refine and optimize therapeutic strategies for AE.
View Article and Find Full Text PDFJACC Clin Electrophysiol
January 2025
Cardioangiologisches Centrum Bethanien, Agaplesion Markus-Krankenhaus, Frankfurt am Main, Germany.
Background: The net benefit of oral anticoagulation in patients with end-stage renal disease on hemodialysis (HD) is uncertain. In recent years, left atrial appendage closure (LAAC) has emerged as an alternative to oral anticoagulation; however, there is scant evidence of LAAC in patients on HD.
Objectives: This study aimed to assess the feasibility and safety of LAAC in patients on HD.
Complement Ther Med
January 2025
Department of Psychosocial Rehabilitation, Medical University of Lodz, Poland, Narutowicza 60, 90-136 Lodz, Poland.
Introduction: IBS is a prevalent gut-brain interaction disorder characterized by abdominal pain and altered bowel habits, significantly affecting quality of life (QoL). IBS contributes to substantial work absenteeism and economic burdens and often coexists with other somatic and psychiatric conditions, with psychological well-being being a critical determinant of QoL. IBS sufferers often turn to MT due to dissatisfaction with conventional treatments.
View Article and Find Full Text PDFAnnu Rev Clin Psychol
January 2025
Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; email:
The opioid crisis, driven by illicitly manufactured fentanyl, presents significant challenges in treating opioid use disorder (OUD) and opioid withdrawal syndrome. Fentanyl is uniquely lethal due to its rapid onset and respiratory depressant effects, driving the surge in overdose deaths. This review examines the limitations of traditional diagnostic criteria like those of the , Fifth Edition, Text Revision (DSM-5-TR) and explores the potential of dimensional models such as the Hierarchical Taxonomy of Psychopathology (HiTOP) for a more nuanced understanding of OUD.
View Article and Find Full Text PDFCien Saude Colet
January 2025
Departamento de Nutrição e Saúde, Universidade Federal de Viçosa. Viçosa MG Brasil.
This article describes the construction and validation of an instruction manual geared toward nutritional care (NC) for people with severe obesity in the Brazilian Unified Health System (SUS). In the production of this instruction manual, a broad literature review was conducted for the identification and discussion of topics to be treated. The content and appearance validity were conducted according to the Delphi technique and to focus groups, respectively, with evaluators who were nutritionists and practitioners, from different regions of Brazil.
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