The juxtaoral organ (JOO) is a vestigial anatomical structure which is not usuallydescribed in lectures and classic texts of general histology and oral histology, despiteit being included in the "Terminologia Histologica: International terms for humancytology and histology". Although there is evidence about its histological structure,there are no macroscopic anatomical reports about it. We report the finding ofa structure of glandular macroscopic appearance in a horizontal section of a plastinatedhuman head belonging to the Morphology Laboratory of the Department ofBiomedical Basic Sciences at the University of Talca. Due to its location, dimensionsand anatomical relations, we determined it to be the JOO. Using a digital calliper, wemeasured the anteroposterior and transverse dimensions of the JOO and observedits anatomical relationships with neighbouring structures of clinical relevance. Weconclude that the JOO is relevant to surgical practice due to its anatomical relationswith relevant structures such as inferior third molar and lingual nerve. Its clinicalapplication lies in the differential diagnosis with invasive processes of malignantneoplasia originating in the oral cavity.
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http://dx.doi.org/10.5603/FM.a2019.0008 | DOI Listing |
Rom J Morphol Embryol
November 2023
Discipline of Histology, Department of Morphological Sciences, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania;
The paper provides an overview of the current understanding of different cells' biology (e.g., keratinocytes, Paneth cells, myoepithelial cells, myofibroblasts, chondroclasts, monocytes, atrial cardiomyocytes), including their origin, structure, function, and role in disease pathogenesis, and of the latest findings in the medical literature concerning the brown adipose tissue and the juxtaoral organ of Chievitz.
View Article and Find Full Text PDFDiagnostics (Basel)
February 2022
Anatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
The juxtaoral organ was first described 1885 as a rudimentary structure that developed and disappeared in the embryonic period. Since then, it has been studied further and is now known to be a permanent anatomical structure of considerable importance in clinical, surgical and pathological fields. However, there are no precise and uniform descriptions about its anatomical localization and functional significance.
View Article and Find Full Text PDFOral Dis
January 2023
Facultad de Medicina, Departamento de Anatomía y Embriología, Universidad Complutense de Madrid, Madrid, Spain.
Front Cell Dev Biol
February 2021
Buchmann Institute for Molecular Life Sciences and Institute of Biochemistry II, Medical Faculty, Goethe University Frankfurt, Frankfurt, Germany.
Cephalization is a major innovation of animal evolution and implies a synchronization of nervous system, mouth, and foregut polarization to align alimentary tract and sensomotoric system for effective foraging. However, the underlying integration of morphogenetic programs is poorly understood. Here, we show that invagination of neuroectoderm through polarization and apical constriction creates the mouth opening in the embryo.
View Article and Find Full Text PDFAnn Anat
November 2020
Departamento de Morfología y Biología Celular, Grupo SINPOS, Universidad de Oviedo, Spain; Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago de Chile, Chile. Electronic address:
Background: The Chievitz's organ or juxta-oral organ is a mysterious bilateral structure, phylogenetically preserved, which develops from the mouth epithelium as an invagination that loses connection to it in the prenatal period. It is located laterally to the walls of the oral cavity in an imprecise anatomical location and receives abundant innervation from the buccal nerve. Structurally it consists of non-keratinizing squamous-like neuroepithelial cells surrounded by two layers of connective tissue with nerve fibers and different morphotypes of sensory corpuscles.
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