Objective: Introduction: The reform of primary health care (PHC), the introduction of market mechanisms in health care, and the consequent change in the status of primary health care institutions require new approaches to the organization and management of the sector. This work is related to various aspects of health care reform: organizational, medical, social, production, financial, economic, etc. The aim of the research is to substantiate the need to apply the principles of business planning for the reform of PHC, in particular: аs a method of strategic planning and operational management of the production activities of a medical institution, аs a way of preventing and solving problems arising from the reform of the industry, аs an instrument for attracting external capital required for project implementation, аs a way of development of personal managerial qualities of the authors of the project - the head of a medical institution and his deputies.
Patients And Methods: Materials and methods: In preparing the article, the following materials and methods were used: survey methods, structural modeling, financial analysis, observation, comparison. Analysis was conducted on the basis of materials of accounting and financial reporting of medical institutions.
Results: Review: The practical implementation of any innovation project is much more complicated or even impossible without a well-designed business plan. The business plan is necessary not only for the justification of commercial activity, but for the implementation of non-commercial projects in order to achieve certain social outcomes. The business plan formulates the main purpose, directions of activity, ways and means of solving problems, and describes the market, production, organizational and financial aspects of future business, as well as features of management. The more dynamic and uncertain the external economic environment, the more attention should be paid to developing a strategic plan. The success of the innovation project is impossible without a clear idea of the prospects of the activity and the real plan of management.
Conclusion: Conclusions: In this article we considered the feasibility of using the principles of business planning in the process of reforming primary health care.
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Infect Dis (Lond)
January 2025
Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, USA.
Background: Whether a detected virus or bacteria is a pathogen that may require treatment, or is merely a commensal 'passenger', remains confusing for many infections. This confusion is likely to increase with the wider use of multi-pathogen PCR.
Objectives: To propose a new statistical procedure to analyse and present data from case-control studies clarifying the probability of causality.
J Ultrasound
January 2025
Argentinian Critical Care Ultrasonography Association (ASARUC), Buenos Aires, Argentina.
Hepatic gas gangrene (HGG) is a rare but life-threatening condition typically caused by anaerobic bacteria such as Clostridium perfringens, though Gram-negative bacteria like Escherichia coli and Klebsiella species have also been implicated. Traditionally diagnosed via computed tomography (CT), point-of-care ultrasound (POCUS) has emerged as a valuable tool in critical care settings for its non-invasive, bedside utility. We report the case of a 51-year-old female with choledochal syndrome secondary to cholangiocarcinoma who developed HGG following left extended hepatectomy and biliary reconstruction.
View Article and Find Full Text PDFKidney Int
January 2025
Laboratório de Fisiopatologia Renal (LIM 16), Nephrology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), Universidade de São Paulo, São Paulo, Brazil. Electronic address:
In 2017, Kidney Disease: Improving Global Outcomes (KDIGO) published a Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). Since then, new lines of evidence have been published related to evaluating disordered mineral metabolism and bone quality and turnover, identifying and inhibiting vascular calcification, targeting vitamin D levels, and regulating parathyroid hormone. For an in-depth consideration of the new insights, in October 2023, KDIGO held a Controversies Conference on CKD-MBD: Progress and Knowledge Gaps Toward Personalizing Care.
View Article and Find Full Text PDFCytotherapy
January 2025
Osteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute, University Health Network, Toronto, Ontario, Canada; Krembil Research Institute, University Health Network, Toronto, Ontario, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; Department of Medicine, Division of Hematology, University of Toronto, Toronto, Ontario, Canada. Electronic address:
The December 2024 US Food and Drug Administration (FDA) approval of Mesoblast's Ryoncil (remestemcel-L-rknd)-allogeneic bone marrow mesenchymal stromal cell (MSC(M)) therapy-in pediatric acute steroid-refractory graft-versus-host-disease finally ended a long-lasting drought on approved MSC clinical products in the United States. While other jurisdictions-including Europe, Japan, India, and South Korea-have marketed autologous or allogeneic MSC products, the United States has lagged in its approval. The sponsor's significant efforts and investments, working closely with the FDA addressing concerns regarding clinical efficacy and consistent MSC potency through an iterative process that spanned several years, was rewarded with this landmark approval.
View Article and Find Full Text PDFIntroduction: In natural disasters, children encounter serious health problems.
Method: This qualitative phenomenological study investigated the problems encountered by children with a diagnosis of celiac disease who lived in the earthquake region of Kahramahmaras in Turkey. Colaizzi method, a phenomenological research method, was used in the study.
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