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Are we cultivating the perfect storm for a human avian influenza pandemic?
Biol Res
December 2024
Laboratory of Cellular and Molecular Inmunology, Fundacion Ciencia & Vida, Universidad San Sebastian, Avda. del Valle Norte 725, Huechuraba, 8580702, Santiago, Region Metropolitana, Chile.
The emergence of highly pathogenic avian influenza (HPAI) A H5N1 virus in dairy cattle marks a troubling new chapter in the ongoing battle against zoonotic diseases. Since its initial detection in 1955, the H5N1 virus has primarily been associated with poultry, posing significant threats to both animal and human health. However, recent outbreaks in U.
View Article and Find Full Text PDFSupercritical CO-Mediated Decellularization of Bovine Spinal Cord Meninges: A Comparative Study for Decellularization Performance.
ACS Omega
December 2024
Regenerative Biomaterials Laboratory, Department of Bioengineering, Faculty of Engineering, Canakkale Onsekiz Mart University, Canakkale 17100, Turkey.
The extracellular matrix (ECM) of spinal meninge tissue closely resembles the wealthy ECM content of the brain and spinal cord. The ECM is typically acquired through the process of decellularizing tissues. Nevertheless, the decellularization process of the brain and spinal cord is challenging due to their high-fat content, in contrast to the spinal meninges.
View Article and Find Full Text PDFReducing antimicrobial use in livestock alone may be not sufficient to reduce antimicrobial resistance among human infections: an ecological study in the Netherlands.
Epidemiol Infect
November 2024
Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Article Synopsis
- The study explores the relationship between antimicrobial use (AMU) in livestock and antimicrobial resistance (AMR) in human infections in the Netherlands from 2004 to 2020.
- It finds that while AMU in livestock is decreasing, AMR among human infections is still increasing, indicating that reducing livestock AMU alone may not effectively combat AMR in humans.
- The research highlights the need for further investigation into the genetic and evolutionary factors contributing to AMR, suggesting that a broader strategy may be needed to address this public health issue.
"Should we just stop fighting the beast?": Tackling the wicked problem of surplus dairy calf management using a participatory framework.
Animal
December 2024
Animal Welfare Program, Faculty of Land and Food Systems, The University of British Columbia, 2357 Main Mall, Vancouver, BC V6T 1Z6, Canada. Electronic address:
Early life killing of male and female dairy calves not needed as replacements for the lactating herd poses a threat to the social sustainability of the dairy industry. However, implementing sustainable alternatives to this common practice is a complex challenge exhibiting many characteristics of a 'wicked problem'. Addressing these problems requires understanding the needs of a wide range of actors including farmers, their advisors, beef and dairy value chain stakeholders, the public, and the animals.
View Article and Find Full Text PDFSurvey in ruminants from Rwanda revealed high diversity and prevalence of extended-spectrum cephalosporin-resistant Enterobacterales.
BMC Vet Res
November 2024
Institute of Microbiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Article Synopsis
- Antimicrobial resistance (AMR) in Enterobacterales, particularly in Escherichia coli, poses serious health and economic issues for humans and animals, highlighting the "One Health" approach to understanding this problem.
- The study aimed to find extended-spectrum cephalosporin-resistant Enterobacterales in ruminants across Rwanda's provinces and to characterize the isolates.
- From 454 rectal swabs collected from cattle, goats, and sheep, 64 resistant isolates were found, predominantly E. coli, with many showing multidrug-resistance and various resistance phenotypes linked to specific genes.
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