AI Article Synopsis
- A 24-year-old pregnant woman showed symptoms of cat scratch disease including fever, fatigue, and vision issues after feeding a feral dog.
- Her initial serum tests were negative for the common strain of Bartonella henselae but positive for a newly identified strain (YH-01) specific to Japan.
- The study suggests that using an IFA assay for the YH-01 strain, or a combination with the Houston-1 strain, could improve the diagnosis of cat scratch disease in Japan.
Article Abstract
Purpose: To report a case of cat scratch disease-associated retinitis diagnosed with an indirect fluorescent antibody (IFA) assay for immunoglobulin M (IgM) specific for a strain (YH-01) of Bartonella henselae recently identified in Japan.
Methods: Case report of a 24-year-old pregnant woman presented with general fever, fatigue, as well as blurred vision, and a central visual field deficiency in her right eye and was suspected as cat scratch disease because she had started to feed a feral dog a month ago.
Results: The patient's serum tested negative, however, with an IFA assay for IgG or IgM specific for the Houston-1, common strain of B. henselae. Further testing with an IFA assay for IgM specific for the YH-01 strain yielded a positive result. On the basis of the clinical findings and the IFA results, we were thus able to make a definitive diagnosis of cat scratch disease.
Conclusion: An IFA assay based on the YH-01 or combination of both YH-01 and Houston-1 strains of B. henselae may show increased sensitivity for the diagnosis of cat scratch disease in Japan.
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| http://dx.doi.org/10.1097/ICB.0000000000000854 | DOI Listing |
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