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Operationalising a Haemophilia Gene Editing Lexicon for Practical Use.
Haemophilia
January 2025
Medicine and Pathology, Georgetown University, Washington, District of Columbia, USA.
Introduction: Gene editing therapies offer the possibility of substantial improvement in treatment and quality of life for people with haemophilia (PWH) in a landscape of dynamic therapeutic advancement. Developing a common and understandable language to discuss gene editing will be essential to ensure these treatments can be deployed in a safe and effective manner with fully informed and shared decision-making between healthcare professionals (HCPs) and PWH. A lexicon explaining and clarifying key concepts is one potential tool to address these aims.
View Article and Find Full Text PDFNutritional Interventions to Attenuate Quadriceps Muscle Deficits following Anterior Cruciate Ligament Injury and Reconstruction.
Sports Med
January 2025
School of Behavioural and Health Sciences, Australian Catholic University, Melbourne, VIC, Australia.
Following anterior cruciate ligament (ACL) injury, quadriceps muscle atrophy persists despite rehabilitation, leading to loss of lower limb strength, osteoarthritis, poor knee joint health and reduced quality of life. However, the molecular mechanisms responsible for these deficits in hypertrophic adaptations within the quadriceps muscle following ACL injury and reconstruction are poorly understood. While resistance exercise training stimulates skeletal muscle hypertrophy, attenuation of these hypertrophic pathways can hinder rehabilitation following ACL injury and reconstruction, and ultimately lead to skeletal muscle atrophy that persists beyond ACL reconstruction, similar to disuse atrophy.
View Article and Find Full Text PDFNeuroscience Literacy and Academic Outcomes: Insights from a University Student Population.
Brain Sci
January 2025
Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
There is growing interest in neuroscience-informed education, as well as neuroscience-derived strategies that maximise learning. Studies on neuroscience literacy and neuromyths, i.e.
View Article and Find Full Text PDFIntegrated health and nutrition approaches to school feeding: maximising future human capital in Latin America and the Caribbean.
Front Public Health
January 2025
Social Protection and Nutrition Unit, Programme Division, World Food Programme, Panama City, Panama.
Integrated health and nutrition packages in schools have been shown to be a cost-effective approach to support children's well-being and academic achievement; yet few countries adequately invest in promoting such integration. School feeding programmes in Latin America are among the best-established, with some of the largest scale and coverage in the world. National School Meal programmes in Latin America and the Caribbean benefit over 80.
View Article and Find Full Text PDFThe COVID-19 pandemic and Urology - reflecting on successful initiatives and lessons in Australia.
BJU Int
January 2025
Department of Urology, Austin Health, Heidelberg, Victoria, Australia.
Objectives: To summarise the impact of the coronavirus disease 2019 (COVID-19) pandemic on urological practice globally with a focus on Australian initiatives, as the pandemic resulted in radical changes in healthcare infrastructure and policies.
Methods: We conducted a literature review of the Medical Literature Analysis and Retrieval System Online (MEDLINE), Excerpta Medica dataBASE (EMBASE) and Web of Science medical databases. The key terms used to conduct our search algorithm comprised of 'COVID', 'wait list or wait time or delay', 'urology', 'surgery' and 'outcomes', and generated 231 articles.
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