We present a case of necrobiosis lipoidica (NL) of the right abdomen in a 75-year-old man. A skin biopsy performed showed a layered infiltrate of mono and multinucleated histiocytes palisaded around degenerated collagen bundles. Laboratory workup was unremarkable. The patient was treated with topical corticosteroids with cessation of progression of his disease, although the eruption did not resolve. There are a number of treatments for NL reported in the literature, all with varying efficacy. Although NL lesions are usually asymptomatic, patients with NL must be monitored closely for signs of ulceration or malignant transformation, in which case more aggressive treatment options may be warranted.
Download full-text PDF |
Source |
---|
Indian J Dermatol
October 2024
Department of Pathology, Command Hospital, Kolkata, West Bengal, India.
JID Innov
November 2024
Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix, Arizona, USA.
J Allergy Clin Immunol
November 2024
Department of Dermatology, Yale School of Medicine, New Haven, Conn; Department of Pathology, Yale School of Medicine, New Haven, Conn. Electronic address:
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!