AI Article Synopsis
- A post-mass drug administration (MDA) survey in Amhara, Ethiopia, assessed self-reported side effects after a 2016 trachoma treatment with azithromycin among 16,773 individuals.
- The overall prevalence of side effects was reported at 9.6%, with abdominal pain being the most common (53.1%), followed by nausea and vomiting.
- Women reported higher side effect rates than men, and the prevalence increased with age, but overall, side effects were low even after 8 years of annual treatment.
Article Abstract
A region-wide population-based post-mass drug administration (MDA) coverage survey was conducted 3 weeks following the 2016 trachoma MDA in Amhara, Ethiopia. The prevalence of self-reported side effects was assessed among those who self-reported receiving azithromycin. A total of 16,773 individuals from 5,129 households reported taking azithromycin during the 2016 MDA in Amhara. The regional prevalence of any self-reported side effect was 9.6% (95% CI: 8.3-11.2%) and ranged from 3.9% to 12.4% among the 10 zones. The most common reported side effects were abdominal pain (53.1%), nausea (21.7%), vomiting (12.8%), and diarrhea (12.5%). Side-effect prevalence among female members was higher than in male members (11.6% versus 7.6%; < 0.001) and increased with age. After an average of 8 years of annual MDA, the prevalence of self-reported side effects was less than 10% in this population.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402909 | PMC |
| http://dx.doi.org/10.4269/ajtmh.18-0781 | DOI Listing |
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