AI Article Synopsis
- Poly(vinyl alcohol) (PVA) is a low-toxicity, biocompatible polymer that can form physically cross-linked gels through hydrogen bonds without a cross-linking agent.
- New research highlights a type of PVA gel called cast-drying on freeze-thawed hybrid gels, which exhibits superior friction properties, making it a promising candidate for artificial cartilage applications.
- The study also examines the effects of gamma ray sterilization on these gels, finding optimal irradiation conditions to maintain their excellent friction characteristics for potential clinical use.
Article Abstract
Poly(vinyl alcohol) (PVA) is a biocompatible polymer with low toxicity. It is possible to prepare physically cross-linked PVA gels having hydrogen bonds without using a cross-linking agent. The newly reported physically cross-linked PVA cast-drying (CD) on freeze-thawed (FT) hybrid gel has an excellent friction property, which is expected to be applied as a candidate material for artificial cartilage. Gamma ray sterilization for clinical applications usually causes additional chemical cross-linking and changes physical properties of gels. In this study, CD on FT hybrid gels were irradiated using gamma rays at a different dose rate and irradiance. The results showed the optimized irradiation conditions for gamma irradiated gels to retain excellent friction characteristics.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209256 | PMC |
| http://dx.doi.org/10.3390/gels4020030 | DOI Listing |
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