Mucormycosis is an uncommon aggressive fungal infection usually seen in immunocompromised hosts or patients with burns and trauma. The common presentations include rhino-orbital-cerebral and pulmonary involvement. Osteoarticular involvement is a rare presentation of this disease. We present two cases of osteoarticular mucormycosis of pelvis and long bones of the lower limb, one in a patient with burn injury and other one in a patient with chronic granulomatous disease, hitherto a rarely reported association. Delayed diagnosis in a setting where tuberculosis is a common cause of chronic osteomyelitis, challenges in medical and surgical management of these patients are discussed in this report.
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http://dx.doi.org/10.5582/ddt.2018.01064 | DOI Listing |
Expert Rev Anti Infect Ther
December 2024
Alfa Institute of Biomedical Sciences, Athens, Greece.
Introduction: Tedizolid is a novel antibiotic of the class ofoxazolidinones. This review evaluates the published literature on the optic andperipheral neuropathy associated with short and prolonged administration oftedizolid.
Areas Covered: A review of published data from 4 databases was conducted,regarding the development of optic and peripheral neuropathy in patients whoreceived tedizolid for short or prolonged duration.
Curr Rev Musculoskelet Med
December 2024
Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, USA.
Purpose Of Review: For pediatric osteomyelitis and septic arthritis, 10-24% of cases occur in the upper extremity (UE). Due to delays in presentation and diagnosis, UE infections are often more complex and severe than infections of the lower extremity (LE). This review evaluates the literature from the past 6 years related to pediatric osteomyelitis and septic arthritis of the UE and provides a guide for professionals managing these conditions in children.
View Article and Find Full Text PDFGMS J Med Educ
December 2024
Orthopedic Surgery Department, Centre Hospitalier Régional Universitaire (CHRU) de Tours, Tours, France.
Objective: Management of osteoarticular infections (OAI) represents a major public health challenge. To deal with this, the French Ministry of Health created the (CRIOAC) in 2008. CRIOAC functions as a national network of reference centers for OAI, with the aim of coordinating, providing expertise, offering training, and conducting research at the regional level.
View Article and Find Full Text PDFCureus
November 2024
Division of Orthopaedic Surgery, Tokyo Women's Medical University, Tokyo, JPN.
Few neonatal cases of soft tissue and osteoarticular infections with have been reported. We report a rare clinical presentation of necrotizing fasciitis of the foot caused by in a 17-day-old male neonate with hypoplastic left-sided heart syndrome. Fulminant progressive black skin necrosis was triggered by fresh frozen plasma leakage from the peripheral venous access.
View Article and Find Full Text PDFMed J Islam Repub Iran
August 2024
Department of Clinical Disciplines, Al-Farabi Kazakh National University, Almaty, Kazakhstan.
Background: High titers of specific antibodies to cyclic citrulline peptide (ACCP) are often present in the serum of patients with rheumatoid arthritis (RA) and, together with rheumatoid factor (RF), are a diagnostic marker of RA. Brucellosis is a zoonotic infection in which osteoarticular involvement occurs in 10-85% of patients. RF in brucellosis patients is significantly higher than in healthy people.
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