Pruritus, impaired mental health and inflammation contribute to morbidity in end-stage renal disease. There are no studies on all 3 conditions. We therefore obtained inflammatory parameter data (C-reactive protein and interleukin-6), pruritus data and psychological test data (36-Item Short-Form Health Survey, "Allgemeine Depressionsskala" and Toronto Alexithymia Scale-20) for 19 dialysis patients with pruritus, 20 dialysis patients without pruritus and 15 healthy controls. Non-parametric hierarchical clustering revealed 3 clusters of parameters: one mainly driven by pruritus scores (chronic kidney disease-associated pruritus cluster), one by mental health scores (mental health cluster) and one by inflammatory parameters (inflammatory cluster). Factor analysis showed strong associations (mental health cluster/chronic kidney disease-associated pruritus cluster, r=-0.49; mental health cluster/inflammatory cluster, r=-0.52; inflammatory cluster/chronic kidney disease-associated pruritus cluster, r=0.48). For the first time, complete correlations between inflammation, mental health and pruritus in dialysis patients have been established. As all 3 conditions are associated with mortality, knowledge about their interdependence helps to understand end-stage renal disease pathophysiology.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2340/00015555-3128 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Addressing the Effect of Exercise on Glial Cells: Focus on Ependymal Cells.
J Integr Neurosci
December 2024
Department of Biomedical and Biotechnological Sciences, Section of Anatomy, Histology and Movement Science, School of Medicine, University of Catania, 95123 Catania, Italy.
A growing body of research highlights the positive impact of regular physical activity on improving physical and mental health. On the other hand, physical inactivity is one of the leading risk factors for noncommunicable diseases and death worldwide. Exercise profoundly impacts various body districts, including the central nervous system.
View Article and Find Full Text PDFFamily Functioning, Anxiety and Depression in Chinese Higher Vocational School Students: A Network Analysis.
Psychol Res Behav Manag
December 2024
Department of Psychiatry, Sleep Medical Center, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Purpose: Network analysis is a statistical method that explores the complex interrelationships among variables by representing them as nodes and edges in a network structure. This study aimed to examine the interconnections between family functioning, anxiety, and depression among vocational school students through network analysis approach.
Participants And Methods: A sample of 2728 higher vocational school students participated in a survey utilizing the Family APGAR Index Questionnaire (APGAR), Generalized Anxiety Disorder Scale (GAD-7), and Patient Health Questionnaire (PHQ-9).
What Outcomes Are Associated with Learning About Colonialism and Its Impacts on Indigenous Peoples in Health Professional Programs? A Critical Integrative Review.
Perspect Med Educ
December 2024
Department of Neuroscience at Carleton University, Carleton University, Ottawa, Ontario, Canada.
Background: The Truth and Reconciliation Commission of Canada called upon health professional programs to teach about historical and on-going colonalism. Since these calls to action, there has been an increase in educational opportunities on the topic. Although it is generally assumed that learning about colonialism will reduce racism and improve allyship towards Indigenous Peoples, an evaluation of this assumption is needed.
View Article and Find Full Text PDFDifferences in smoking cessation behaviors and vaping status among adult daily smokers with and without depression, anxiety, and alcohol use: Findings from the 2018 and 2020 International Tobacco Control Four Country Smoking and Vaping (ITC 4CV) Surveys.
Int J Ment Health Addict
December 2024
Department of Psychology, University of Waterloo, Waterloo, ON, Canada.
This study examined differences in quit attempts, 1-month quit success, and vaping status at follow-up among a cohort of 3709 daily smokers with and without depression, anxiety, and regular alcohol use who participated in both the 2018 and 2020 International Tobacco Control Four Country Smoking and Vaping (ITC 4CV) Surveys. At baseline, a survey with validated screening tools was used to classify respondents as having no, or one or more of the following: 1) depression, 2) anxiety, and 3) regular alcohol use. Multivariable adjusted regression analyses were used to examine whether baseline (2018) self-report conditions were associated with quit attempts; quit success; and vaping status by follow-up (2020).
View Article and Find Full Text PDFGender-specific perception of job stressors and resources: a structural equation model-based secondary analysis.
Front Public Health
December 2024
Department of Fitness and Health, IST University of Applied Sciences, Düsseldorf, Germany.
Objective: Stress is an extensive issue in modern society, affecting men and women differently. A better understanding of these patterns is required within the work context. Therefore, this study aimed to identify gender differences in the effects of stressors (quantitative demands, qualitative demands, working time) and resources (job control, quality of leadership, co-worker support) on subjective perceived stress across occupational groups.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!