When the human mind is free to roam, its subjective experience is characterized by a continuously evolving stream of thought. Although there is a technique that captures people's streams of free thought-free association-its utility for scientific research is undermined by two open questions: (a) How can streams of thought be quantified? (b) Do such streams predict psychological phenomena? We resolve the first issue-quantification-by presenting a new metric, "forward flow," that uses latent semantic analysis to capture the semantic evolution of thoughts over time (i.e., how much present thoughts diverge from past thoughts). We resolve the second issue-prediction-by examining whether forward flow predicts creativity in the lab and the real world. Our studies reveal that forward flow predicts creativity in college students (Study 1) and a representative sample of Americans (Study 2), even when controlling for intelligence. Studies also reveal that membership in real-world creative groups-performance majors (Study 3), professional actors (Study 4) and entrepreneurs (Study 5)-is predicted by forward flow, even when controlling for performance on divergent thinking tasks. Study 6 reveals that forward flow in celebrities' social media posts (i.e., on Twitter) predicts their creative achievement. In addition to creativity, forward flow may also help predict mental illness, emotional experience, leadership ability, adaptability, neural dynamics, group productivity, and cultural success. We present open-access online tools for assessing and visualizing forward flow for both illustrative and large-scale data analytic purposes. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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PLoS One
January 2025
School of Civil Engineering, Guizhou University, Guiyang, Guizhou, China.
The mechanical properties of jointed rock bodies are important in guiding engineering design and construction. Using the particle flow software PFC2D, we conducted direct shear test simulations on joints with various inclinations and five different roughness levels to examine the models' crack extension penetration paths, damage modes, and strength characteristics. The findings indicate that the direction of the joint influences the pattern of the rock crack and its penetration route.
View Article and Find Full Text PDFAnn Card Anaesth
January 2025
Department of Cardiothoracic and Vascular Anaesthesia, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
Background: This study aimed to assess the accuracy of tricuspid spectral Doppler (E/A) and tissue Doppler parameters (E/E') to diagnose right ventricular diastolic dysfunction (RVDD) in comparison to American Society of Echocardiography (ASE criteria) in pediatric tetralogy of Fallot (TOF) patients after surgical repair.
Methods: This prospective, observational study was done at a tertiary care hospital involving 40 pediatric TOF patients aged less than 2 years who underwent complete intracardiac repair with cardiopulmonary bypass (CPB). Echocardiographic observations were made using a pediatric transesophageal echocardiography probe after surgical repair in the post-CPB period.
Phytomedicine
January 2025
Post-graduate Department of Biotechnology, Utkal University, Bhubaneswar, 751004, Odisha, India.; Centre of Excellence in Integrated Omics and Computational Biology, Utkal University, Bhubaneswar 751004, Odisha, India.. Electronic address:
Background: Cardiovascular diseases (CVDs) are the major contributor to global mortality and are gaining incremental attention following the COVID-19 outbreak. Epigenetic events such as DNA methylation, histone modifications, and non-coding RNAs have a significant impact on the incidence and onset of CVDs. Altered redox status is one of the major causative factors that regulate epigenetic pathways linked to CVDs.
View Article and Find Full Text PDFBMC Chem
January 2025
Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.
White and Green Analytical Chemistry are innovative approaches in analytical chemistry that prioritize both sustainability and efficiency. Together, these approaches aim to advance scientific research while minimizing environmental impact and enhancing safety. This integration of environmental consciousness into analytical practices represents a significant step forward in achieving sustainable scientific progress.
View Article and Find Full Text PDFDose Response
January 2025
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Cytokinins are plant hormones that regulate cell growth and differentiation. In particular, zeatin (ZTN) delays cellular senescence of human fibroblasts and keratinocytes and exhibits anticancer activity. Chemotherapy-induced anemia is a major side effect of anticancer therapy secondary to premature senescence of red blood cells (RBCs).
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