Introduction: The purpose of this study was to review our recent experience of salvage surgery, comparing larynx and oropharynx recurrence patterns.
Methods: A single centre, retrospective review of salvage surgery for recurrent head and neck cancer including patients between 2008 and 2016.
Results: 61 patients were identified, 36 underwent salvage laryngectomy and 25 received oropharyngeal resections. The median overall survival of oropharyngeal recurrent tumors was 26 months (95% CI 15-118 months) and for laryngeal tumors was 23 months (95% CI 11-38 months), p = 0.1008. There was a significant overall survival benefit in patients with negative resection margin. The median survival in the negative margin group was 38 months (95% CI 25-108 months) compared to the positive margin group, 9 months (95% CI 5-15 months), p < 0.0001.
Conclusion: Survival results following surgical salvage in the larynx and oropharynx appear to be similarly poor. Those patients with clear margins appear to have a significantly better prognosis.
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http://dx.doi.org/10.1007/s00405-019-05295-x | DOI Listing |
Am J Cancer Res
December 2024
Department of Oncology, Dongying District People's Hospital 333 Jinan Road, Dongying District, Dongying, Shandong, China.
The use of routine adjuvant radiotherapy (RT) after breast-conserving surgery (BCS) is controversial in elderly patients with early-stage breast cancer (EBC). This study aimed to evaluate the efficacy of adjuvant RT for elderly EBC patients using deep learning (DL) to personalize treatment plans. Five distinct DL models were developed to generate personalized treatment recommendations.
View Article and Find Full Text PDFTaiwan J Ophthalmol
January 2024
Department of Ophthalmology, National Taiwan University Hospital, Yunlin Branch, Yunlin, Taiwan.
Purpose: The aim of this study was to propose a simplified segmental scleral buckling (SSSB) technique that does not require break localization for less-experienced vitreoretinal surgeons.
Materials And Methods: This retrospective study compared the clinical results of 46 conventional and 23 SSSB (conventional segmental SB [CSSB] and SSSB, respectively) procedures in a tertiary referral retinal center in Taiwan between 2008 and 2019. In the CSSB group, breaks were localized during surgery.
Taiwan J Ophthalmol
October 2023
Department of Vitreo-Retina, Disha Eye Hospitals, Kolkata, West Bengal, India.
Closure rate of full-thickness macular holes (FTMHs) with basal diameter >1000 μ is known to be poor. Patients presenting with FTMH having a minimum basal diameter of >1000 μ without any coexistent retinal morbidity were offered vitrectomy, internal limiting membrane peeling, retinal massage, and aspiration of subretinal fluid from the MH. Visual acuity (VA) and spectral-domain optical coherence tomography (SD OCT) assessments were performed at baseline, week 1 after surgery and at postoperative months 1, 3, 6, and 12.
View Article and Find Full Text PDFTher Adv Neurol Disord
January 2025
Department of Neurology, The Second Hospital of Hebei Medical University, 215 Heping West Road, Shijiazhuang, Hebei 050000, P.R. China.
Background: Amyotrophic lateral sclerosis (ALS) is a rapidly progressing and rare neurodegenerative disease. Therefore, evaluating the risk factors affecting the survival of patients with ALS is crucial. Constipation, a common but overlooked symptom of ALS, can be effectively managed.
View Article and Find Full Text PDFFood Sci Nutr
January 2025
Department of Food Science and Technology, Faculty of Technical and Engineering University of Science and Arts of Yazd Yazd Iran.
In this study, minced turkey meat samples were subjected to electron-beam irradiation with dosages of 0, 1.5, 3, and 5 kGy, and then microbial (mesophilic and psychrotrophic bacteria), physiochemical (pH, water activity [a], thiobarbituric acid reactive substances [TBARS], and peroxide value [PV]), and sensory (color, odor, texture, and overall acceptability) analyses were performed at 0 and 6 months of freezing storage (-18°C). Results showed that by 5 kGy irradiation and freezing treatments, the counts of psychrotrophic and mesophilic bacteria reduced remarkably ( < 0.
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