Outcomes of salvage surgery for the oropharynx and larynx: a contemporary experience in a UK Cancer Centre.

Eur Arch Otorhinolaryngol

Head and Neck Surgery Department, Guys and St Thomas' NHS Trust, Great Maze Pond, London, SE1 9RT, UK.

Published: April 2019

Introduction: The purpose of this study was to review our recent experience of salvage surgery, comparing larynx and oropharynx recurrence patterns.

Methods: A single centre, retrospective review of salvage surgery for recurrent head and neck cancer including patients between 2008 and 2016.

Results: 61 patients were identified, 36 underwent salvage laryngectomy and 25 received oropharyngeal resections. The median overall survival of oropharyngeal recurrent tumors was 26 months (95% CI 15-118 months) and for laryngeal tumors was 23 months (95% CI 11-38 months), p = 0.1008. There was a significant overall survival benefit in patients with negative resection margin. The median survival in the negative margin group was 38 months (95% CI 25-108 months) compared to the positive margin group, 9 months (95% CI 5-15 months), p < 0.0001.

Conclusion: Survival results following surgical salvage in the larynx and oropharynx appear to be similarly poor. Those patients with clear margins appear to have a significantly better prognosis.

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Source
http://dx.doi.org/10.1007/s00405-019-05295-xDOI Listing

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