AI Article Synopsis
- ACE inhibitors (ACE-I) are commonly prescribed for conditions like high blood pressure, heart failure, and heart attacks.
- Despite their benefits, about 20% of patients stop taking ACE-I due to side effects, particularly chronic cough.
- The review will explore the debated mechanisms behind ACE-I-induced cough and highlight current research on this issue.
Article Abstract
Angiotensin-converting enzyme inhibitors (ACE-I) are widely used in diseases, such as hypertension, congestive heart failure, and myocardial infarction. Although these drugs are well tolerated, one out of five patients discontinues ACE-I due to drug side effects, mainly chronic cough. However, the pathogenesis of ACE-I-induced cough remains controversial and requires further study. In this review, the mechanisms that are suggested in ACE-I-induced cough pathophysiology will be discussed in detail in light of the current literature.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340691 | PMC |
| http://dx.doi.org/10.5152/TurkThoracJ.2018.18014 | DOI Listing |
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