The indoor environment contributes considerably to human exposure to poly- and perfluoroalkyl substances (PFASs). This study estimated the human exposure to PFASs from the indoor environment through hand-to-mouth and dermal contacts using hand wipes. An analytical method was developed to determine 25 PFASs in hand wipe samples collected as a composite sample from both hands of 60 adults. Polyfluoroalkyl phosphate esters (PAPs) were the predominant PFASs in the hand wipe samples (medians between 0.21 and 0.54 ng per sample). Positive and significant correlations were observed between PAPs, perfluorooctanesulfonate (PFOS), and perfluorooctanoate (PFOA) in hand wipes. Low frequency of daily hand washing (≤8 times day) was associated with 30-50% higher concentrations of PFOS, PFOA, and 8:2diPAP in hand wipes. Further, significant correlations between paired hand wipes and house dust samples were observed for PFOS, PFOA, and 6:2diPAP. Also, a significant correlation between PFOS in hand wipes and EtFOSE in indoor air was found. This finding indicates either a common source of exposure or a transformation of EtFOSE to PFOS in the environment or on the hands. The contributions of direct and indirect exposure to perfluoroalkyl acids (PFAAs) showed that PFOA contributed the highest exposure to adults via hand-to-mouth and dermal contacts, followed by PFOS. The median of estimated daily intakes via hand-to-mouth and dermal contacts (for hands only) for PFOA were 0.83 and 0.50 pg·kg bw·day, respectively. This study gives a first indication that PFAS concentrations in hand wipes can be used as a proxy for the exposure to PFASs from indoor environments, but further studies are needed to confirm this.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.est.8b05303 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
HBM4EU chromates study: the Portuguese integrated and harmonized study on exposure to hexavalent chromium and related early effects.
Ann Work Expo Health
December 2024
National Institute of Health Dr. Ricardo Jorge (INSA), Avenida Padre Cruz, 1649-016 Lisbon, Portugal.
In the scope of the European Union (EU) human biomonitoring initiative, a multicentric study on different occupational settings from several European countries was performed, to provide information on occupational exposure to hexavalent chromium [Cr(VI)], a known lung carcinogen. Biomonitoring approaches were used to obtain exposure data to support the implementation of new risk management measures and policy actions at the national and European levels. This work describes the Portuguese contribution to the study, which aimed to assess workers' exposure to Cr, by using exposure biomarkers (urinary chromium [U-Cr]), and industrial hygiene samples (air and hand wipes) and to link exposure to potential long-term health effects by using effect biomarkers.
View Article and Find Full Text PDFEvaluating lay first responder (LFR) first aid kit supplies usage and appropriateness in Western Kenya.
Pan Afr Med J
December 2024
Lay First Responders International, Los Angeles, California, United States of America.
Introduction: low- and middle-income countries (LMICs) disproportionately bear 90% of global mortality from trauma, yet robust emergency medical services (EMS) are often lacking to address the prehospital injury burden. Training lay-first responders (LFRs) is the first step toward formal (EMS) development in (LMICs). However, a gap remains as LFR first aid kit supply usage, appropriateness, and decay rates have yet to be studied but remain critical information for building sustainable LFR programs.
View Article and Find Full Text PDFRescue and Translocation of Hispaniola Hutia () in Pueblo Viejo, Cotuí Mining Concession Area.
Ecol Evol
November 2024
Barrick Pueblo Viejo Dominicana Jersey 2 Limited Pueblo Viejo Dominican Republic.
Translocation of species is a common practice used in endangered species management and conservation plans, which can have the purpose of establishing new populations which are at risk of being wiped out, increase a species chance of survival or recovery, and to preserve genetic diversity. The present study details the rescue and relocation process of Hispaniola Hutia () in the municipality of Cotuí, Dominican Republic. Data are presented for eight individuals, belonging to two different families, detailing capture methods, handling, reintroduction method, and behavior, as well as data on post-release monitoring for both families.
View Article and Find Full Text PDFHuman bare and clothing-covered skin exposure to chlorinated paraffins for the general populations: Exposure pattern differential and significance of indirect dermal exposure via clothing-to-skin transport.
Environ Int
October 2024
Guangdong Provincial Key Laboratory of High-Quality Recycling of End-of-Life New Energy Devices, Guangzhou Institute of Energy Conversion, Chinese Academy of Sciences, Guangzhou 510640, China. Electronic address:
Article Synopsis
- A study assessed human exposure to short-chain and medium-chain chlorinated paraffins (SCCPs and MCCPs) through skin contact and hand-to-mouth activities by analyzing wipes from the faces, arms, hands, and feet of 30 volunteers.
- The findings showed that hands had the highest concentrations of these compounds, suggesting that direct contact with indoor surfaces plays a significant role in skin contamination.
- Notably, the study revealed that dermal absorption rates were much higher than those from oral ingestion, indicating that skin contact is a major exposure route for these chemicals in humans.
Appropriate Hand Drying - The Missed Step of Hand Hygiene: A Qualitative Evaluation of Hand Drying Practices among Indian Health Care Workers.
Indian J Community Med
July 2024
Department of Neonatology, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India.
Hand hygiene remains one of the most effective methods of preventing healthcare-associated infections. Hand drying is the end point of hand hygiene. Hand drying after hand hygiene is less explored, and the practice varies in different facilities.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!