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Explainable Artificial Intelligence for Predicting Attention Deficit Hyperactivity Disorder in Children and Adults.
Healthcare (Basel)
January 2025
Research, Development, and Innovation Laboratory, Mundiapolis University, Casablanca 20180, Morocco.
Attention Deficit Hyperactivity Disorder (ADHD) is a disorder that starts in childhood, sometimes persisting into adulthood. It puts a strain on their social, professional, family, and environmental lives, which can exacerbate disorders such as anxiety, depression, and bipolar disorder. : This paper aims to predict ADHD in children and adults and explain the main factors impacting this disorder.
View Article and Find Full Text PDFA Retrospective Analysis of the Impact of Electroconvulsive Therapy on Anxiety Symptoms in Patients With Treatment-Resistant Depression.
J ECT
January 2025
From the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA.
Background: Electroconvulsive therapy (ECT) is an effective treatment for treatment-resistant depression (TRD). There are limited data on the improvement of anxiety symptoms in patients receiving ECT for TRD.
Objective: The aim of the study was to examine the extent to which anxiety symptom severity improves, relative to improvements in depressive symptoms, in TRD patients receiving an acute course of ECT.
Investigating the Shared Genetic Architecture Between Psychiatric Disorders and Executive Function.
Biol Psychiatry Glob Open Sci
November 2024
Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Background: Evidence for widespread comorbidity of executive dysfunctions with psychiatric disorders suggests common mechanisms underlying their pathophysiology. However, the shared genetic architectures between psychiatric disorders and executive function (EF) remain poorly understood.
Methods: Leveraging large genome-wide association study datasets of European ancestry on bipolar disorder ( = 353,899), major depressive disorder ( = 674,452), and schizophrenia ( = 130,644) from the Psychiatric Genomics Consortium and iPSYCH and a common factor of EF ( = 427,037) from UK Biobank, we systematically investigated the shared genomic architectures between psychiatric disorders and EF with a set of statistical genetic, functional genomic, and gene-level analyses.
Clinical Interplay Between Autism Spectrum Disorder and Bipolar Disorder: A Narrative Review.
Trends Psychiatry Psychother
January 2025
Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil. Graduate Program in Psychiatry and Behavioral Sciences, Department of Psychiatry and Legal Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil. National Institute of Science and Technology for Translational Medicine (INCT-TM), Porto Alegre, RS, Brazil. Faculty of Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Canada.
Introduction: Autism Spectrum Disorder (ASD) and Bipolar Disorder (BD) present significant challenges in diagnosis due to their complex nature. This review aims to examine the interface and overlapping features of these conditions.
Methods: We conducted a narrative review to examine clinical overlap, common psychiatric comorbidities, and shared neurobiological bases between ASD and BD.
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