Boron-associated shifts in sex ratios at birth were suggested earlier and attributed to a decrease in Y- vs. X-bearing sperm cells. As the matter is pivotal in the discussion of reproductive toxicity of boron/borates, re-investigation in a highly borate-exposed population was required. In the present study, 304 male workers in Bandirma and Bigadic (Turkey) with different degrees of occupational and environmental exposure to boron were investigated. Boron was quantified in blood, urine and semen, and the persons were allocated to exposure groups along B blood levels. In the highest ("extreme") exposure group (n = 69), calculated mean daily boron exposures, semen boron and blood boron concentrations were 44.91 ± 18.32 mg B/day, 1643.23 ± 965.44 ng B/g semen and 553.83 ± 149.52 ng B/g blood, respectively. Overall, an association between boron exposure and Y:X sperm ratios in semen was not statistically significant (p > 0.05). Also, the mean Y:X sperm ratios in semen samples of workers allocated to the different exposure groups were statistically not different in pairwise comparisons (p > 0.05). Additionally, a boron-associated shift in sex ratio at birth towards female offspring was not visible. In essence, the present results do not support an association between boron exposure and decreased Y:X sperm ratio in males, even under extreme boron exposure conditions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00204-019-02391-z | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Analysis of Toxic Element Levels and Health Risks in Different Soybean Species (, , , ).
Nutrients
December 2024
Toxicology Area, University of La Laguna, Tenerife, Canary Islands, 38071 La Laguna, Spain.
Soybeans are a widely consumed legume, essential in Western diets and especially prominent in vegan and vegetarian nutrition. However, environmental contamination from anthropogenic sources, such as industrial emissions, wastewater, and pesticide use, has led to the accumulation of non-essential and toxic elements in legumes, potentially impacting human health. This study quantified the levels of 11 potential toxic elements (Al, B, Ba, Cd, Co, Cr, Li, Ni, Pb, Sr, V) in 90 samples of four soybean species (, , , ) using inductively coupled plasma optical emission spectrometry (ICP-OES).
View Article and Find Full Text PDFCurrent Insights into the Radiobiology of Boron Neutron Capture Therapy and the Potential for Further Improving Biological Effectiveness.
Cells
December 2024
Department of Cancer and Genomic Sciences, College of Medicine and Health, University of Birmingham, Birmingham B15 2TT, UK.
Photon (X-ray) radiotherapy is the most common treatment used in cancer therapy. However, the exposure of normal tissues and organs at risk to ionising radiation often results in a significant incidence of low-grade adverse side effects, whilst high-grade toxicities also occur at concerningly high rates. As an alternative, boron neutron capture therapy (BNCT) aims to create densely ionising helium and lithium ions directly within cancer cells, thus sparing the surrounding normal cells and tissues but also leading to significantly more effective tumour control than X-rays.
View Article and Find Full Text PDFVisible-Light-Fueled Polymerizations for 3D Printing.
Acc Chem Res
January 2025
Department of Chemistry, The University of Texas at Austin, 105 East 24th Street, Austin, Texas 78712, United States.
ConspectusLight-driven polymerizations and their application in 3D printing have revolutionized manufacturing across diverse sectors, from healthcare to fine arts. Despite the popularized notion that with 3D printing "imagination is the only limit", we and others in the scientific community have identified fundamental hurdles that restrict our capabilities in this space. Herein, we describe the group's efforts in developing photochemical systems that respond to nontraditional colors of light to elicit the rapid, spatiotemporally controlled formation of plastics.
View Article and Find Full Text PDFUnravelling the Epitaxial Growth Mechanism of Hexagonal and Nanoporous Boron Nitride: A First-Principles Microkinetic Model.
Small
January 2025
School of Chemistry and Chemical Engineering, University of Surrey, GU2 7XH, Guildford, UK.
Article Synopsis
- The study uses density functional theory and microkinetic modeling to analyze the growth of hexagonal boron nitride (hBN) on a ruthenium surface, focusing on the process of chemical vapor deposition (CVD).
- Four main stages of the growth process are detailed: adsorption and deprotonation of borazine, dimerization, stabilization of larger borazine polymers, and the formation of nanoporous intermediates.
- Findings highlight the importance of the deprotonation sequence in nanostructure formation and provide insights for producing high-quality hBN monolayers, aligning well with experimental data for temperature variations and precursor exposure.
Roadmap for Borophene Gas Sensors.
ACS Sens
January 2025
Chimie des Interactions Plasma Surface group, Chemistry Department, Université de Mons, 7000 Mons, Belgium.
Borophene, a two-dimensional allotrope of boron, has emerged as a promising material for gas sensing because of its exceptional electronic properties and high surface reactivity. This review comprehensively overviews borophene synthesis methods, properties, and sensing applications. However, it is crucial to acknowledge the substantial gap between the abundance of theoretical literature and the limited experimental studies.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!